Espinel VML, Martín JJA, Jiménez PR, Vázquez NS, Díaz LA

Language: Spanish
References: 16
Page: 28-31
PDF size: 100.33 Kb.

ABSTRACT

A patient with cancer of the lung who developed a persistent erythematous eruption overling the injected vein induced by perfusion of vinorelbine is reported. No evidence of superficial phlebitis or extravasation were observed. Histologic features were consistent with erythema multiforme –like reaction (localized epidermal necrolysis) with abnormalities of the maduration of keratinocytes, eccrine neutrophilic hidradenitis and squamous syringometaplasia.
This pathologic alterations are almost diagnostic of a citotoxic chemotherapeutic reaction and we think this case could be diagnostic as a persistent supravenous erythematous eruption.

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