medigraphic.com
ISSN 1561-302X (Print)

2012, Number 3

<< Back Next >>

Rev cubana med 2012; 51 (3)

Clinical, endoscopic and histological characterization of raised diminutive colon lesions

Hano GOM, González FL, Fernández CJÁ, Hierro GA

Language: Spanish
References: 17
Page: 218-227
PDF size: 71.40 Kb.


ABSTRACT

Introduction: raised diminutive colon lesions are of great interest due to their frequent appearance in endoscopic procedures and their association with adenomatous lesions.
Objective: carry out a clinical, endoscopic and histological characterization of this type of lesions.
Methods: an observational descriptive cross-sectional study was conducted at the Institute of Gastroenterology from January 2007 to June 2009. The sample consisted of 249 raised diminutive colon lesions found in 193 patients aged 18 and over. These patients underwent colonoscopy and biopsies were taken from their lesions.
Results: there was a prevalence of the 50-69 age group, female sex and white skin color. Most patients were asymptomatic and the colon disease most commonly associated was polyps. The most common locations were the sigmoid colon and the rectum, with a prevalence of ≤ 2 mm and > 4-5 mm lesions. Most lesions were non-neoplastic and all adenomas were tubular. Low-grade dysplasia was the most common.


REFERENCES

  1. Beers MH, Porter RS, Jones TV, Kaplan JL, Berkwits M, editores. Cáncer colorrectal. En: El Manual Merck de diagnóstico y tratamiento. 11ª ed. Madrid: Elsevier, 2007:189.

  2. Landis SH, Murray T, Bolden S, Wingo P. Cancer statistics, 1999. CA Cancer J Clin. En. Feb. 1999;49(1):8-31.

  3. República de Cuba. Dirección Nacional de Estadísticas. Anuario estadístico del 2007: Mortalidad por algunos tumores malinos según sexo. [en línea]. La Habana: MINSAP; 2008. [consultado Mar 2009] Disponible en:http://bvs.sld.cu/cgibin/wxis/anuario/?IsisScript=anuario/iah.xis&base=anuario&lang=e

  4. Surveillance Epidemiology and End results (SEER). National Cáncer Institute. [consultado Ene 2009] Disponible en:http://seer.cancer.gov/statfacts/htm/colorect.html

  5. Kudo S. Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc. 1996;44(1):8-14.

  6. Steven H Itzkowitz. Pólipos colónicos y síndromes polipósicos. En: Feldman M, Friedman LS, Sleisenger MH. Enfermedades gastrointestinales y hepáticas. 7ma. ed. Buenos Aires: Médica Panamericana; 2004.p. 2324-27.

  7. Unal H, Selcuk H, Hale Gokcan H, Tore E, Sar A, Korkmaz M et al. Malignancy risk of small polyps and related factors. Dig Dis Sci. 2007;52(10):2796-9.

  8. Declaración de Helsinki de la Asamblea Médica Mundial. Principios éticos para las investigaciones médicas en seres humanos. 52a Asamblea General [monografía en Internet]. Escocia: Asamblea Médica Mundial; 2000 [consultado feb 2009]. Disponible en:http://www.upo.es/general/ investigar/otri/otri_docu/pn/Decl_Helsinki.pdf

  9. De Palma GD, Rega M, Masone S, Persico M, Siciliano S, Addeo P, et al. Conventional colonoscopy and magnified chromoendoscopy for the endoscopic histological prediction of diminutive colorectal polyps: a single operator study. World J Gastroenterol. 2006;12(15):2402-5.

  10. Read TE, Read JD, Butterly LF. Importance of adenomas 5 mm or less in diameter that are detected by sigmoidoscopy. N Engl J Med. 1997;336(1):8-12.

  11. Sciallero S, Bonelli L, Aste H, Casetti T, Bertinelli E, Bartolini S, et al. Do patients with rectosigmoid adenomas 5 mm or less in diameter need total colonoscopy? Gastrointest Endosc. 1999;50(3):31421.

  12. Lieberman D, Moravec M, Holub J, Michaels L, Eisen G. Polyp size and advanced histology in patients undergoing colonoscopy screening: Implications for CT colonography. Gastroenterology. 2008;135(4):1100-5.

  13. Brooker JC, Saunders BP, Shah SG, Thapar CJ, Thomas HJ, Atkin WS, et al. Total colonic dye-spray increases the detection of diminutive adenomas during routine colonoscopy: a randomized controlled trial. Gastrointestinal Endosc. 2002;56(3):3338.

  14. Butterly LF, Chase MP, Pohl H, Fiarman GS. Prevalence of Clinically Important Histology in Small Adenomas. Clin Gastroenterol Hepatol. 2006;4(3):3438.

  15. Barreda F, Combe J, Valdez LA, Sánchez J. Aspectos Clínicos de los pólipos colónicos. Rev Gastroenterol Perú. 2007;27:131-47.

  16. Nusko G, Mansmann U, Altendorf-Hofmann A, Groitt H, Wittekind C, Hahn EG. Risk of invasive carcinoma in colorectal adenomas assessed by size and site. Int J Colorect Dis. 1997;12:26771.

  17. Argyrides J, Lim A, Pietris K. What is the significance of «Diminutive» colonic polyps in patients screened for colon cancer after a positive Faecal Human Haemoglobin test (FHH)? J Gastroent Hepatol. 2011;26 (Suppl. 4):2233.




2020     |     www.medigraphic.com