2012, Number 3
Comparative study on animal model of acute Achilles tendon rupture with surgical treatment using platelet-rich plasma
Hernández-Martínez JC, Vásquez-CR, Ceja-CB, Fuentes-CCE, Sesma-JF, Benítez-AG
Language: Spanish
References: 8
Page: 170-173
PDF size: 34.53 Kb.
ABSTRACT
Objective: To compare the functional and histologicalal course of two animal model groups with acute Achilles tendon tears using platelet rich plasma. Material and methods: An open clinical trial was conducted with dogs donated by the animal facility of the Autonomous University of Puebla (BUAP, for its acronym in Spanish). Dogs were divided into 2 groups: a control group and a problem group. Intentional surgical Achilles tendon tear was performed to them. The Krackow technique was used to repair the tendon and the control group received platelet rich plasma (PRP) as a clot; the other group did not receive PRP. The dogs were seen at 4 weeks to check functionality using he Farell and Schwarz scale to assess the degree of limping. They were sacrificed at week 5; the tendons were removed and sent to the histopathology lab. Results: Functionality results according to the Farell and Schwarz scale showed grades I and II in the problem group, and grades IV and V in the control group. Histologically, the problem group showed moderate vascular proliferation and abundant fibroblastic proliferation. The control group had mild to moderate vascular proliferation and moderate fibroblastic proliferation. Conclusions: PRP improves tendon healing and this has repercussions on functional recovery.REFERENCES