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2009, Number 2

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Rev Med Inst Mex Seguro Soc 2009; 47 (2)

Periventricular Leukomalacia Prevalence in Premature Newborn

Hernández-Cabrera MÁ, Flores-Santos R, García-Quintanilla JF, Hernández-Herrera RJ, Alcalá-Galván LG, Castillo-Martínez NE

Language: Spanish
References: 15
Page: 147-150
PDF size: 68.42 Kb.


ABSTRACT

Background: the periventricular leukomalacia (PLM) is considered a lesion of the central nervous system secondary to a hypoxic-ischemic insult, and affects more to premature than term neonates. However, the reported rates in the literature are between 2 % to 25 % in premature neonates. The objective was to determine the prevalence of PLM in premature neonates.
Methods: a two year prospective screening program with transfontanel ultrasound in premature neonates weighing ‹ 2000 g was carried out at 4 weeks of age.
Results: from 38 355 consecutive deliveries 562 were premature neonates weighted ≤ 2000 g who fulfilled inclusion criteria and all were studied with transfontanel ultrasonography; we found 36 (6.34 %) premature neonates with PLM. Of the 346 neonates weighing ≤ 1500 g, 26 (7.5 %) had a positive examination for PLM. In the 1501 g to 2000 g group, 10 of 216 (4.6 %) had PLM. The PLM prevalence was higher in male (2:1). Neurological exam was normal at the time of study.
Conclusions: the PLM was present in 6.3 % of premature neonates weighing ‹ 2000 g with 2 affected males for each female.


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