2001, Number 2
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An Med Asoc Med Hosp ABC 2001; 46 (2)
Dermatomyositis and gastric cancer as paraneoplastic syndrome
Zabaleta CDP, Serrano A, Gerson R
Language: Spanish
References: 21
Page: 83-87
PDF size: 107.91 Kb.
ABSTRACT
Dermatomyositis is a condition in which the skeletal muscle results affected by an inflammatory process non supurative, manifesting proximal weakness and a characteristic cutaneous eruption. It can be related to viral infection, diseases of the connective tissue as systemic lupus erythematosus, mixed connective tissue and in lesser proportion to neoplasias. A case of dermatomyositis related to gastric adenocarcinoma is reported in a 44 years old man. The incidence is variable from 6% to 43% of the cases when dermatomyositis is associated to neoplasia and this can appear up to 2 years after the miositis has been established, as a case a paraneoplastic syndrome. The neoplasias frequently related are ovarian, breast and lung cancer and digestives as colon cancer and in lesser proportion gastric cancer.
REFERENCES
Callen J. Relationship of cancer to inflammatory muscle disease. Rheum Dis Clin North Am 1994; 20 4): 943-953.
Whitmore S, Rosenshein N et al. Ovarian cancer in patients with dermatomyositis. Medicine 1994: 73 (3); 153-160.
Plotz P, Rider L et al. Myositis: Immunologic contributions to understanding cause, pathogenesis and therapy. Ann Inter Med 1995; 122 (9): 715-724.
Manchul LA, Jin A et al. The frequency of malignant neoplasm in patients with polymiositis-dermatomyositis: A controlled study. Arch Intern Med 1985; 145: 1835-1839.
Targoff I. Immune manifestations of inflammatory muscle disease. Rheum Dis Clin North Am 1994; 20 (4): 857-880.
Dalaskas M. Polymiositis, dermatomyositis, and inclusion body miositis. NEJM 1991; 325(2l): 1487-1498.
Basset-Seguin N et al. Prognostic factors and predictive signs of malignancy in adult dermatomyositis. Arch Dermatol 1990; 126 (5): 633-637.
Sigurgeirsson B, Lindelof B et al. Risk of cancer in patients with dermatomyositis or polymiositis. A population based study. NEJM 1992; 326 (6): 363-367.
Kohy E, Seow A et al. Adult onset polymiositis/dermatomyositis: Clinical and laboraty features and treatment response in 75 patients. Ann Rheum Dis 1993; 52: 857-861.
Zantos D, Zhang Y, Felson D. The overall and tempora1 association of cancer with polymiositis and dermatomyositis. J Rheumatol 1994; 21: 1855-1859.
Cherin P, Piette J et al. Dermatomyositis and ovarian cancer: A report of 7 cases and literature review. J Rheumatol 1993; 20: 1897-1899.
Isselbacher, Braunwald et al. Principios de Medicina Interna. 13 ed. Mexico: Interamericana, 1994; II: 2743-2749.
Kamel OW et al. Lymphoid neoplasm in patients with rheumatoid arthritis dermatomyositis: Frequency of Epstein-Barr virus and other features associated with immunosuppression. Hum Pathol 1994; 25 (7): 638-43.
Stonecipher MR et al. The red face: Dermatomyositis. Clin Dermatol 1993; 11 (2): 261-73.
Bernard P, Bonnetblanc J. Dermatomyositis and malignancy. J Invest Dermatol 1993; 100 (1): 1285-1325.
Callen JP et al. The value of malignancy evaluation in patients with dermatomyositis. J Am Acad Dermatol 1982; 6: 253-259.
Fudman EJ, Schnitzer TJ. Dermatomyositis without creatine kinase elevation. Am J Med 1986; 80: 329-332.
Nicholis D. Dermatomyositis without creatine kinase elevation. Am J Med 1987; 83: 182-183.
Callen JP. Malignancy in polymiositis and dermatomyositis. Clin Dermatol 1988; 2: 55-63.
Callen JP. The relationship of dermatomyositis-polymiositis to malignancy. J Rheumatol 1991; 18: 1645-1646.
Callen J. Dermatomyositis. Lancet 2000; 355: 53-57.