2012, Number 3
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Med Int Mex 2012; 28 (3)
Evaluation of biochemical markers in individuals with severe community-acquired pneumonia by influenza A (H1N1) in Oaxaca, Mexico
Revilla-Rodríguez E, Olvera-Sumano V, Ruiz-Olivera MR, Baltazar-Torres JA, Acosta-Castellanos M, Sánchez-Valencia H, Oscar García-López, Jesús Elizarrarás-Rivas, J Omar López-Ortíz, Barrios-Miranda A, Cerda-Flores RM
Language: Spanish
References: 17
Page: 249-255
PDF size: 297.22 Kb.
ABSTRACT
Background: Seasonal flu is an infectious disease under epidemiological surveillance in México since 1947.
Material and Methods: We performed a retrospective cohort study in three Intensive Care Units (ICU) of Oaxaca, México, by review of patient records in a range of 18 to 70 years, infected by influenza virus A (H1N1) between March 1 and December 31, 2009.
Results: Forty records were reviewed. The average age of patients was 40.68 (± 11.86 years), 57.5% (23) were men and 42.5% (17) women, mean BMI was 33.34% (± 7.3). We found diabetes in 17.5%, hypertension in 10% and obesity in 60% patients. 97.5% required mechanical ventilation (MV) for 15.1 (± 11.72) days, mean 14.38 ± 11.67 days of intensive care staying and 18.88 ± 14.24 of the residence time. Mortality was 67.5%. Comparative analysis at admission and discharge showed significant differences in biochemical makers like leukocyte count and albumin, pH, PaCO2 and bicarbonate levels. Survival group showed significant differences for: MV days, intensive care and residence time as well immature forms in leukocyte count. At discharge there were significant differences in all variables except fibrinogen levels. Ventilator and blood gas parameters had not significant differences in admission, all the discharge values except bicarbonate showed significant differences.
Discussion: The severe community-acquired pneumonia due to influenza A (H1N1) affects young population with comorbidities such as mellitus diabetes, hypertension and obesity, but did not affect mortality. The reported mortality in this paper is similar to previous reports in México.
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