2012, Number 1
<< Back Next >>
Rev Mex Med Transfus 2012; 5 (1)
Staphylococcus capitis isolation from a unit of packed red blood cells implicated in transfusion-associated bacterial sepsis
Cerdas-Quesada C
Language: Spanish
References: 14
Page: 19-23
PDF size: 211.26 Kb.
ABSTRACT
Bacterial contamination of hemocomponents is the leading cause of transfusion related mortality. The culture of components may detect the presence of bacteria, thereby reducing the risk of a septic result after transfusion. Bacteria that contaminate blood products may be originated by donor’s skin flora, an asymptomatic bacteremia or contamination during blood processing. A 35-year-old woman developed fever and hypotension after being transfused with a 25-day-old unit of red blood cells Group O Rh(o)D negative. Subsequent studies from the RBC unit were positive for the presence of
Staphylococcus capitis whereas days after the platelets culturing obtained from the same donation was negative to date in an aerobic bottle. It is necessary to implement an aerobic culture bottle and to review the disinfection techniques of the skin.
REFERENCES
Lee CK, Ho PL, Lee KY, Tsui GT, Chua E, Tsoi WC, Lin CK. Value of anaerobic culture in bacterial surveillance program for platelet concentrates. Transfusion 2008; 48: 2606-11.
Lin CY, Tseng SB, Lu PL, Chen TC, Lin WR, Chen YH, Lin KS. Isolation of Streptococcus bovis from apheresis platelets of asymptomatic donor warranted colonoscopy investigation: case report and literature review. Transfusion 2011; 51: 2023-7.
Cunha G, Leão L, Pimenta F. Bacterial contamination of random-donor platelets in a university hospital in the midwestern region of Brazil. Transfusion 2008; 48: 282-5.
Lessa F, Leparc GF, Benson K, Sanderson R, Van Benedem CA, Shewmaker PL, Jensen B, Arduino MJ, Kuehnert MJ. Fatal group C streptococcal infection due to transfusion of a bacterially contaminated pooled platelet unitdespite routine bacterial culture screening. Transfusion 2008; 48: 2177-83.
Eder AF, Goldman M. How do I investigate septic transfusion reactions and blood donors with culture-positive platelet donations? Transfusion 2011; 51: 1662-8.
Eder AF, Kennedy JM, Dy BA, Notari EP, Skeate R, Bachowski G, Mair DC, Webb JS, Wagner SJ, Dodd RY, Benjamin RJ; American Red Cross Regional Blood Centers. Limiting and detecting bacterial contamination of Apheresis platelets: inlet-line diversion and increased culture volumen improve component safety. Transfusion 2009; 49: 1554-63.
Blajchman MA. Incidence and significance of the bacterial contamination of blood components. Dev Biol (Basel) 2002; 108: 59-67.
Chen CL, Yu JC, Holme S, Jacobs MR, Yomtovian R, McDonald CP. Detection of bacteria in stored red cell products using a culture-based bacterial detection system. Transfusion 2008; 48: 1550-7.
Yomtovian RA, Palavecino EL, Dysktra AH et al. Evolution of surveillance methods for detection of bacterial contamination of platelets in a university hospital, 1991 through 2004. Transfusion 2006; 46: 719-30.
Rao PL, Strausbaugh LJ, Liedtke LA, Srinivasan A, Kuehnert M. Bacterial infections associated with blood transfusion: experience and perspective of infectious diseases consultants. Transfusion 2007; 47: 1206-11.
Robillard P, Delage G, Itaj NK, Goldman M. Use of hemovigilance data to evaluate the effectiveness of diversion and bacterial detection. Transfusion 2011; 51: 1405-11.
Benjamin RJ, Wagner SJ. The residual risk of sepsis: modeling the effect of concentration on bacterial detection in two-bottle culture systems and an estimation of false-negative culture rates. Transfusion 2007; 47: 1381-89.
Brecher ME, Hay SN. Investigation of an isolate of Staphylococcus lugdunensis implicated in a platelet fatality: a possible advantage of the use of an anaerobic bottle. Transfusion 2007; 47: 1390-4.
Bueno JL. Skin disinfection and bacterial contamination of blood components: be simple. Transfusion 2010; 50: 5-8.