medigraphic.com
Boletín Médico del Hospital Infantil de México

2012, Number 2

<< Back Next >>

Bol Med Hosp Infant Mex 2012; 69 (2)

Maternal diet and vitamin D during pregnancy and association with bone health during childhood. Review of the literature

Garza-Gisholt AC, Rivas-Ruiz R, Clark P

Language: English
References: 32
Page: 83-90
PDF size: 185.13 Kb.


Text Extraction

Deficiencies in maternal diet and low maternal plasma of vitamin D in pregnancy may influence the growth and bone mineral accrual of the offspring during fetal life and childhood. This review summarizes the evidence available from cohort studies that include information of maternal diet and concentrations of vitamin D during pregnancy associated with bone mass of the offspring.
A literature search was conducted through MEDLINE and included studies from 2000 to 2009.
The main associations found in the studies were related to maternal calcium intake and vitamin D concentrations. Several studies reported a high prevalence of maternal vitamin D deficiency (varying from 15% to 66%) associated with increased risk of neonatal vitamin D deficiency [odds ratio (OR) 17.2, 95% CI 8.8-34.3)]. A strong positive association between maternal and cord blood serum vitamin D was found in two different studies (r = 0.70 and r = 0.755 p ‹0.001). Mothers who were deficient in vitamin D had offspring with lower whole body bone mineral content (BMC) (mean 1.04 kg ‹ 0·16 vs. 1.16 kg ‹ 0.17, p = 0.002).
Adequate concentrations of maternal vitamin D are essential for calcium homeostasis and bone health of the newborn. High prevalence of maternal vitamin D insufficiency found in different populations can lead to problems of low BMC or, in severe cases, fetal rickets.


REFERENCES

  1. Cooper C. Epidemiology of osteoporotic fracture: looking to the future. Rheumatology (Oxford) 2005;44(suppl 4):iv36-iv40.

  2. Javaid MK, Cooper C. Prenatal and childhood influences on osteoporosis. Best Pract Res Clin Endocrinol Metab 2002;16:349-367.

  3. Cooper C, Fall C, Egger P, Hobbs R, Eastell R, Barker D. Growth in infancy and bone mass in later life. Ann Rheum Dis 1997;56:17-21.

  4. Namgung R, Tsang R. Factors affecting newborn bone mineral content: in utero effects on newborn bone mineralization. Proc Nutr Soc 2000;59:55-63.

  5. Prentice A. Micronutrients and the bone mineral content of the mother, fetus and newborn. J Nutr 2003;133(suppl 2):1693S-1699S.

  6. Abrams S. In utero physiology: role in nutrient delivery and fetal development for calcium, phosphorus, and vitamin D. Am J Clin Nutr 2007;85(suppl):604S-607S.

  7. Prentice A, Jarjou L, Golberg G, Bennett J, Cole TJ, Schoenmakers I. Maternal plasma 25-hydroxyvitamin D concentration and birthweight, growth and bone mineral accretion of Gambian infants. Acta Pædiatr 2009;98:1360-1362.

  8. Ganpule A, Yajnik CS, Fall CH, Rao S, Fisher DJ, Kanade A, et al. Bone mass in Indian children—relationships to maternal nutritional status and diet during pregnancy: the Pune Maternal Nutrition Study. J Clin Endocrinol Metab 2006;91:2994-3001.

  9. Cole ZA, Gale CR, Javaid MK, Robinson SM, Law C, Boucher BJ, et al. Maternal dietary patterns during pregnancy and childhood bone mass: a longitudinal study. J Bone Miner Res 2009;24:663-668.

  10. Jones G, Riley MD, Dwyer T. Maternal diet during pregnancy is associated with bone mineral density in children: a longitudinal study. Eur J Clin Nutr 2000;54:749-756.

  11. Tobias JH, Steer CD, Emmett PM, Tonkin RJ, Cooper C, Ness AR, ALSPAC study team. Bone mass in childhood is related to maternal diet in pregnancy. Osteoporos Int 2005;16:1731-1741.

  12. Javaid MK, Crozier SR, Harvey NC, Gale CR, Dennison EM, Boucher B, et al. Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet 2006;367:36-43.

  13. Gale CR, Robinson SM, Harvey NC, Javaid MK, Jiang B, Martyn CN, et al. Maternal vitamin D status during pregnancy and child outcomes. Eur J Clin Nutr 2008;62:68-77.

  14. Chang SC, O’Brien KO, Sculman NM, Caufield LE, Mancini J, Witter FR. Fetal femur length is influenced by maternal dairy intake in pregnant African American adolescents. Am J Clin Nutr 2003;77:1248-1254.

  15. Godfrey K, Walker-Bone K, Robinson S, Taylor P, Shore S, Wheeler T, et al. Neonatal bone mass: influence of parental birthweight, maternal smoking, body composition, and activity during pregnancy. J Bone Miner Res 2001;16:1694-1703.

  16. Maghbooli Z, Hossein-Nezhad A, Shafaei AR, Karimi F, Madani FS, Larijani B. Vitamin D status in mothers and their newborns in Iran. BMC Pregnancy Childbirth 2007;7:1. doi:10.1186/1471-2393-7-1

  17. Akcakus M, Koklu E, Budak N, Kula N, Kurtoglu S, Koklu S. The relationship between birthweight, 25-hydroxyvitamin D concentrations and bone mineral status in neonates. Ann Trop Paediatr 2006;26:267-275.

  18. Bowyer L, Catling-Paull C, Diamond T, Homer C, Davis G, Craig ME. Vitamin D, PTH and calcium levels in pregnant women and their neonates. Clin Endocrinol 2009;70:372-377.

  19. Morley R, Carlin JB, Pasco JA, Wark JD. Maternal 25-hydroxyvitamin D and parathyroid hormone concentrations and offspring birth size. J Clin Endocrinol Metab 2006;91:906-912.

  20. Mahon P, Harvey N, Crozier S, Inskip H, Robinson S, Arden N, et al. Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res 2010;25:14-19.

  21. Dijkstra SH, van Beek A, Janssen JW, de Vleeschouwer LH, Huysman WA, van der Akker EL. High prevalence of vitamin D deficiency in newborn infants of high-risk mothers. Arch Dis Child 2007;92:750-753.

  22. Bonjour JP, Chevalley T, Ferrari S, Rizzoli R. The importance and relevance of peak bone mass in the prevalence of osteoporosis. Salud Publica Mex 2009;51(suppl 1):S5-S17.

  23. Prentice A, Schoenmakers I, Laskey MA, Bono S, Ginty F, Goldberg GR. Symposium on ‘Nutrition and health in children and adolescents.’ Session 1: Nutrition in growth and development. Nutrition and bone growth and development. Proc Nutr Soc 2006;65:348-360.

  24. Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M, Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 2008;122:398-417.

  25. Huh SY, Gordon CM. Vitamin D deficiency in children and adolescents: epidemiology, impact and treatment. Rev Endocr Metab Disord 2008;9:161-170.

  26. Saintonge S, Bang H, Gerber LM. Implications of a new definition of vitamin D deficiency in a multiracial US adolescents population: The National Health and Nutrition Examination Survey III. Pediatrics 2009;123:797-803.

  27. Specker BL. Does vitamin D during pregnancy impact offspring growth and bone? Proc Nutr Soc 2012;71:38-45.

  28. Hewison M, Adams JS. Vitamin D insufficiency and skeletal development in utero. J Bone Miner Res 2010;25:11-13.

  29. Specker BL. Do North American women need supplemental vitamin D during pregnancy or lactation? Am J Clin Nutr 1994;59(suppl):484S-491S.

  30. Specker BL, Johannsen N, Binkley T, Finn K. Total body bone mineral content and tibial cortical bone measures in preschool children. J Bone Miner Res 2001;16:2298-2305.

  31. Binkovitz LA, Henwood MJ. Pediatric DXA: technique and interpretation. Pediatr Radiol 2007;37:21-31.

  32. Hollis BW, Wagner CL. Nutritional vitamin D status during pregnancy: reasons for concern. CMAJ 2006;174:1287-1290.




2020     |     www.medigraphic.com