medigraphic.com
ISSN 1561-2996 (Electronic)
ISSN 0864-0289 (Print)

2012, Number 2

<< Back Next >>

Rev Cubana Hematol Inmunol Hemoter 2012; 28 (2)

Tests of coagulation and hemostasis components. Usefulness for diagnosing hemorrhagic diathesis

Zamora-González Y

Language: Spanish
References: 22
Page: 141-150
PDF size: 62.07 Kb.


ABSTRACT

Coagulogram comprises a set of tests, which explore the participation of all components of hemostasia: vascular endothelium, platelet activity, plasma and fibrinolytic factors. Often, the technical staff finds complex to do these tests, so deepening knowledge, understanding, and interpreting the results of each of these tests should result in strengthening and training of health professionals. This paper describes the main conventional coagulation tests, the beginning and the reference values of each of them, and the possible diseases according to the alteration of the hemostatic system corresponding to the alteration of coagulation, with the aim of providing medical background information for the proper performance and proper interpretation of results.


REFERENCES

  1. Montiel-Manzano G. Temas selectos de laboratorio e investigación en hematología. VIII. Hemostasia primaria. Gac Med Mex. 2003;139(Supl 2):95-6.

  2. Kordich L, Sánchez Avalos JC, de Campos Guerra C, editores. Manual de hemostasia y trombosis (Grupo CLAHT). 2da. ed. Buenos Aires: Federación Bioquímica;1990.

  3. Chordá C, Páramp JA. The vascular endothelium: physiopathology and participation in thrombogenesis. Sangre. 1995 Dec;40(6):491-8.

  4. Verstraeten L, Francois P, Dinant JP. The physiology of primary hemostasis. J Pharm Belq. 1989 Jul-Aug;44(4):302-7.

  5. Muñoz JA. Anticoagulantes y trombolíticos en anestesia y reanimación. J Anesthesiol. 2007;15:17-26.

  6. Quintana M, Cabestrero D, García de Lorenzo A. Coagulación y hemorragia en el paciente crítico: patrón, pruebas diagnósticas y etiología. Inter Med. 2003;9:605-14.

  7. Duke WW. The relation of blood platelets to hemorrhagic disease. JAMA. 1983 Sep 2;250(9):1201-9.

  8. Kitchen S, McCraw A, Echenagucida M. Diagnosis of hemophilia and other bleeding disorders. Laboratory Manual. 2nd. ed. Montreal-Quebec: World Federation of Hemophilia; 2010.

  9. Duncan SC, Winkelmann RK. Early histopathology of the cutaneous capillary fragility test (Rumpel-Leede). J Cutan Pathol. 1979 Feb;6(1):1-4.

  10. Pavlovsky M. Manual de hemostasia y trombosis (Grupo CLAHT). Buenos Aires: Federación Bioquímica;1990. p. 430.

  11. Evatt BL, Gibbs WN, Lewis SM, Mc Arthur JR. Fundamental diagnostic Hematology. The bleeding and clotting disorders. Georgia: US Deparment of Health and Human Services and World Health Organization;1992. p. 57.

  12. Tocantins LM. Platelets and the spontaneous syneresis of blood clot. Am J Physiol. 1934;110:278.

  13. Brecher G, Scheneiderman M, Conkrite EP. The reproducibility and constancy of the platelet count. Am J Clin Pathol. 1953;23:15.

  14. Lee RI, White PD. A clinical study of the coagulation time of the blood. Am J Med Sc;1913;145:495.

  15. De Bosch Nb, Arocha Piñango CL, Curriel D, Goldestein C. Tiempo de coagulación. En: Kordich L, Sánchez Avalos JC, de Campos Guerra C, editores. Manual de hemostasia y trombosis (Grupo CLATH). Buenos Aires: Federación de Bioquímica;1990. p. 146-7.

  16. Proctor RR, Rapaport SI. The partial thromboplastin time with kaolín. Am J Clin Pathol. 1961;36:212.

  17. Schmaier AH. Laboratory evaluation of hemostatic and thrombotic disorders. En: Hoffman R, Benz EJ Jr, Shattil SJ, et al, editors. Hoffman Hematology: Basic principles and practice. 5th. ed. Philadelphia: Churchill Livingstone Elsevier;2008.

  18. Rubio R, Almagro D, González A, Mesa J, Fonseca C. Sensibilidad del tiempo parcial de tromboplastina activado. Rev Cubana Hematol Inmunol Hemoter. 1986:2:235-42.

  19. Quick AJ. The Thromboplastin reagent for the determination of prothrombin. Science. 1940;92(2379):113-4.

  20. Caen J, Larrieu MJ, Samama M. L´hemostase. Méthodes d' exploration et diagnostic pratique. Paris: L'Expansion Scientifique; 1975. p. 208-9, 348-51.

  21. Samama M, Conard J, Horellou MH, Lecompte T. Physiologie et exploration de I´hémostase. Paris: Doin; 1990. p. 155-6.

  22. Kordich L, editor. Fundamentos para el manejo práctico en el laboratorio de hemostasia. Grupo CAHT. Buenos Aires: Federación de Bioquímica;2003.




2020     |     www.medigraphic.com