Gutiérrez GYI, Miranda MM, Bello AA, Verona HS, Montes de Oca PR

Language: Spanish
References: 18
Page: 405-413
PDF size: 185.31 Kb.

ABSTRACT

The objective of this paper was the chemical characterization of two extracts from Phyllanthus orbicularis HBK through gas chromatography/mass spectrometry. To this end, maceration with N-hexane and ethyl acetate was used to obtain the respective extracts. The study of the hexane extract identified 17 components in which hydrocarbonate structures prevailed, mainly cyclooctacosane. In the ethyl acetate extract, 19 compounds were detected, being the terpenoids the predominant, although the most abundant was sterol ã-sitosterol. For the first time, the identified compounds are reported for this species.

REFERENCES

1. Roig JT. Diccionario botánico de nombres vulgares cubano. La Habana: Editorial Científico Técnica; 1988. p. 80.

2. Del Barrio G, Parra F. Evaluation of the antiviral activity of an aqueous extract from Phyllanthus orbicularis. J Ethnopharmacol. 2000;72:317-22.

3. Fernández J, Del Barrio G, Romeo B, Gutiérrez Y, Valdés S, Parra F. In vitro antiviral activity of Phyllanthus orbicularis extract againts herpes simples type 1. Phytother Res. 2003;17:980-2.

4. Valdés S, Del Barrio G, Gutiérrez Y, Morier L. Evaluación preliminar de la actividad del extracto acuoso de Phyllanthus orbicularis frente al virus VHS-1. Rev Cubana Med Trop. 2003;55(3):169-73.

5. Ferrer M, Sánchez A, Fuentes J, Barbé J, Llagostera M. Antimutagenic mechanisms of Phyllanthus orbicularis when hydrogen peroxide is tested using Salmonella assay. Short communication. Mut Res. 2002;517:251-4.

6. Sánchez AL, Fuentes JL, Fonseca G, Cápiro N, Ferrer M, Alonzo A, et al. Assessment of the potential genotoxic risk of Phyllantus orbicularis HBK aqueous extract using in vitro and in vivo assays. Toxicol Letters. 2002;136:87-96.

7. Berazaín R, Fuente V, Sánchez D, Rufo L, Rodríguez N, Amils R. Nickel localization on tissues of hyperaccumulator species of Phyllanthus L. (Euphorbiaceae) from ultramafic areas of Cuba. Biol Trace Elem Res. 2007;115:67-86.

8. Álvarez A, Del Barrio G, Kouri V, Martínez P, Suárez B, Parra F. In vitro antiherpetic activity of an aqueous extract from the plant Phyllanthus orbicularis. Phytomedicine. 2009;16(10):960-6.

9. Nurettin Y, Canan G, Osman Ü, Ahmet Y, Serdar Ü, Kamil C, et al. Composition and Antimicrobial Activities of Volatile components of Minuartia meyeri. Turk J Chem. 2006;30:71-7.

10. Silverstein RM, Bassler CG, Morrill TC. Spectrometric identification of organic compounds. 3rd ed. La Habana: Edición Revolucionaria; 1977. p. 5-38.

11. Calixto JB, Adair RS, Valdir CF, Rosendo AY. A review of the plants of the genus Phyllanthus: Their chemistry, pharmacology and therapeutic potential. Med Res Rev. 1998;18(4):225-58.

12. Stuart KL, Ivonne GW. Further effects of vomifoliol on stomatal apertura ando n the germination of Lettuce and the Growth of cucumber seedlings. Planta (Berl.). 1975;127:21-5.

13. Kuete V, Ngameni B, Fotso Simo C, Kengap R, Tchaleu B, Meyer M, et al. Antimicrobial activity of the crude extracts and compounds from Picus chlamydocarpa and Picus cordata (Moraceae). J Ethnopharmacol. 2008;120(1):17-24.

14. Budzikiewicz H, Wilson JM, Djerassi C. Mass spectrometry in structural and stereochemical problems. XXXII. Pentacyclic Triterpenes.1963;85:3688-99.

15. Hinge VK, Paknikar S K, Das KG, Bose AK. and Bhattacharyya. Terpenoids- LXXXVI. Structure of Epi-ø-Taraxastanonol and Epi-ø-Taraxastanediol. Tetrahedron. 1966;22:2861-8.

16. Anjaneyulu V, Satyanarayana P, Viswanadham K, Jyothi V. Triterpenoids from Mangifera indica. Phytochemistry. 1999;50:1229-36.

17. Pascual TJ, Urones JG, Marcos IS, Basabe P, Sexmero MJ, Fernández RM. Triterpenes from Euphorbia broteri. Phytochemistry. 1987;26(6):1767-76.

18. Toshihiro A, Ken Y, Hirotoshi O, Yoshimasa K, Sakae Y, Michio T, et al. Triterpene alcohols from the flower of compositae and their anti-inflammatory effects. Phytochemistry. 1996;43(6):255-1260.