2011, Number 1
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Rev Cubana Estomatol 2011; 48 (1)
Odontogenic carcinoma of clear cells
Flores ASA; Morales CJ; Sepúlveda IR; Romero DE
Language: Spanish
References: 26
Page: 69-76
PDF size: 168.71 Kb.
ABSTRACT
Clear cell odontogenic carcinoma is a rare malignant odontogenic neoplasm, with a
predilection for the anterior segment of the jaws, and presenting basically in
women between the fifth and seventh decades of life. CCOC is composed
histopathologycally by strands or groups of cells showing clear cytoplasm
associated with cells showing eosinophilic cytoplasm and some times with tall
columnar cells that resambled ameloblasts. CCOC is considered a low-grade
malignancy but in some cases its behavior is aggressive giving local and distant
metastasis, so the recommended treatment is a radical resection and follows the
patient very close. CCOC should be diferenciated microscopically from other local
and metastatic lesions that are composed with clear cells also, in order to render a
proper diagnosis and treatment. We are presenting a clinical case corresponding to
a 69 years old female patient, with a 10 year history of a slow growing anterior
mandibular lesion without lymph node or distant metastasis, with a biopsy
diagnosis of clear cell odontogenic carcinoma, the patient was treated by partial
resection of the anterior mandible and reconstructed with a titanium plate.
REFERENCES
Reichart PA, Philipsen HP. Odontogenic tumors and allied lesions. Quintessence Publishing. 2004. p. 239-47, ISBN 1850970599.
Waldron CA, Small SA, Silverman H. Clear cell ameloblastoma: an odontogenic carcinoma. J Oral Maxillofac Surg. 1985;43:707-17.
Madhu K. Nair E, Burkes J. Onanong Chai-U-Dom. Radiographic manifestation of clear cell odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;89:250-4.
Maiorano E, Altini M, Viale G, Piattelli A, Favia G. Clear cell odontogenic carcinoma. Report of two cases and review of the literature. Am J Clin Pathol. 2001; 116:107-14.
Dahiya S, Kumar R, Sarkar C, Ralte M, Sharma MC. Clear cell odontogenic carcinoma: a diagnostic dilemma. Pathology oncology research. 2002;8(4):283-5.
August M, Faquin W, Troulis M, Kaban L. Clear cell odontogenic carcinoma: Evaluation of reported cases. J Oral Maxillofac Surg. 2003;61:580-6.
Avninder S, Rakheja D, Bhatnagar A. Clear cell odontogenic carcinoma: a diagnostic and therapeutic dilemma. World Journal of Surgical Oncology. 2006;4:91.
Braunshtein E, Vered M, Taicher S, Buchner A. Clear cell odontogenic carcinoma and clear cell ameloblastoma: A single clinicopathologic entity? A new case and comparative analysis of the literature. J Oral Maxillofac Surg. 2003;61:1004-10.
Regezi JA. Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws. Modern Pathology. 2002;15(3):331.
Mosqueda-Taylor A, Meneses-García A, Ruíz-Godoy LM, Suárez-Roa ML, Luna- Ortiz K. Tumores odontogénicos malignos. Estudio retrospectivo y colaborativo de 7 casos. Medicina Oral. 2003;8:110-21.
Chera BS, Villaret DB, Orlando CA, Mendenhall WM. Clear cell odontogenic carcinoma of the maxilla: a case report and literature review. Am J Otolaryngol. 2008;29(4):284-90.
Xavier FC, Rodini CO, Ramalho LM, Sarmento VA, Nunez FD, de Sousa SC. Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(3):403-10.
Ebert CS Jr, Dubin MG, Hart CF, Chalian AA, Shockley WW. Clear cell odontogenic carcinoma: a comprehensive analysis of treatment strategies. Head Neck. 2005;27(6):536-42.
Goldenberg D, Sciubba J, Koch W. Tufano RP. Malignant odontogenic tumors: a 22 years experience. Laryngoscope. 2004;114(10):1770-4.
Siriwardena BS, Tilakaratne Wm, Rajapaksha RM. Clear cell odontogenic carcinoma_a case report and review of literature. Int J Oral Maxillofac Surg. 2004;33(5):512-4.
Jundt G, Reichart PA. Malignant odontogenic tumors. Pathologe. 2008.
Kumar M, Fasanmade A, Barrett AW, Mack G, Newman L, Hyde NC. Metastasing clear cell odontogenic carcinoma: a case report and review of the literature. Oral Oncol. 2003;39(2):190-4.
Mosqueda-Taylor A, Meneses-García A, Ruíz-Godoy LM, Suárez-Roa LM. Clear cell odontogenic carcinoma of the mandible. J Oral Pathol Med. 2002;31(7):439-41.
Brandwein M, Said-Al-Naief N, Gordon R, Urken M. Clear cell odontogenic carcinoma: report of a case and analysis os the literature. Arch Otolaryngol Head Neck Surg. 2002;128(9):1089-95.
Eversole LR. Malignant epithelial odontogenic tumors. Semin Diagn Pathol. 1999;16(4):317-24.
Yamamoto H, Inui M, Mori A, Tagawa T. Clear cell odontogenic carcinoma: A case report and literature review of odontogenic tumors with clear cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;86(1):86-9.
Maiorano E, Altini M, Favia G. Clear cell tumors of the salivary glands, jaws and oral mucosa. Semin Diagn Pathol. 1997;14(3):203_12.
Muramatsu T. Hashimoto S, Inoue T, Shimono M, Noma H, Shigematsu T. Clear cell odontogenic carcinoma in the mandible: histochemical and immunohistochemical observations with a review of the literature. J Oral Pathol Med. 1996;25(9):516-21.
Marí A, Escutia E, Carrera M, Pericot J. Clear cell ameloblastoma or odontogenic carcinoma. A case report. J Craniomaxillofac Surg. 1995;23(6):387-90.
Eversole LR. On the differential diagnosis of clear cell tumours of the head and neck. Eur J Cancer B Oral Oncol. 1993;29(3):173-9.
Milles M, Doyle JL, Mesa M, Raz S. Clear cell odontogenic carcinoma with lymph node metastasis. Oral Surg Oral Med Oral Pathol. 1993;76(1):82-9.