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2008, Number 5

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Rev Med Inst Mex Seguro Soc 2008; 46 (5)

Pleural Mesothelioma in a Mexican Population: Clinical and Radiological 561 Similarities Among Histopathologic Patterns

Pérez-Guzmán C, Vargas MH, Torre-Bouscoulet L

Language: Spanish
References: 29
Page: 561-566
PDF size: 111.58 Kb.


ABSTRACT

Objective: to describe clinical and radiological features of patients with pleural mesothelioma, according to main histological types.
Methods: clinical records of inpatients admitted with diagnosis of pleural mesothelioma to the Instituto Nacional de Enfermedades Respiratorias in the last 11 years, were reviewed.
Results: we analyzed 85 cases confirmed by immunohistochemistry. The most frequent histological type was epithelial (84.7 %), followed by sarcomatous (12.9 %) and mixed (2.4 %) types. Comparison between epithelial and sarcomatous types showed no differences in age (53.7 ± 13.1 vs. 55.9 ± 11.0 years, respectively), male:female ratio (2.3:1 vs. 1.8:1), history of asbestos exposure (34.7 vs. 27.2 %), tobacco habit (54.2 vs 45.4 %), occupation, evolution time (4.8 ± 3.3 vs. 4.4 ± 3.7 months), pain, dyspnea and cough, right-side predominance (55.6 vs. 81.8 %), radiological image with pleural effusion (59.7 vs. 36.4 %) or pleural thickening (38.9 vs. 63.6 %), and diagnostic efficiency of closed pleural biopsy (58.3 vs. 27.2 %).
Conclusions: our results suggest that clinical and radiological features of epithelial and sarcomatous histological types are very similar. Additionally, we found a high frequency of epithelial mesothelioma, which contrasts with findings from other countries, suggesting that the type of asbestos or other factors involved in the development of pleural mesothelioma differ from those existing in other regions of the world.


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