2000, Number 3
<< Back Next >>
Cir Cir 2000; 68 (3)
Pott’s disease: a diagnostic and therapeutic challenge for present-day medicine
Torre-González D, Góngora-López J, Huerta-Olivares V, Pérez-Meave JA
Language: Spanish
References: 22
Page: 108-113
PDF size: 568.87 Kb.
ABSTRACT
The objective of the study is to apply a new diagnostic method for Pott’s Disease, in less time and fewer major surgeries. The finality is to give the patient medical treatment to improve of the disease.
Patient and method: Prospective study, descriptive, longitudinal, and observational with 32 patients, average age, 48 years (20-76 years). There were 17 males (58.12%) and 15 females (46.98%). The period covered June 1994 to June 1999, with selective judgement of the patient to be included in the study.
The affected levels of Pott’s disease: Thoracic, 53%; lumbar, 28%, and thoracic lumbar, 19%.
Diagnosis: we carried out in each patient a systemic study including the following:
Laboratory: Bh, Baar in mucosity and urine; cultivation urine and mucosity; Immunological: PPD, ELISA for Ag Tb, Immunochromatography and PCR and Other: Rx, TAC on RNM.
Relation of the study results:
• ELISA 15 patients (46%).
• Immunochromatography 12 patients (39%).
• PCR 4 patients (15%).
Treatment: Giving the patient medical treatment with antibiotics. The surgical treatment came later but in some cases depending of the indications made on anterior approach, the finality to was decompress and stabilize the column.
The following review for 2-year evaluation, 12 months with antibiotic, and the release of a new chromatography to observation erradication and Rx.
Discussion: We offer a diagnostic method that is more efficient and that avoids the complications that Pott’s Disease presents using the PCR and chromatography, and includes follow up of the patient.
Evaluation of the eradication of the infection of Mycobacterium was carried out 12 months after the treatment.
REFERENCES
Block AB et al. The epidemiology of tuberculosis in the United States. Implications for diagnosis and clinical treatment. Chest Med 1989; 10: 297-318.
Chu JB. Treatment of spinal tuberculosis in Korea using focal debridement and interbody fusion. Clin Orthop 1968; 50: 235-253.
Janssen JP et al. Spinal tuberculosis in a developed country. A review of 26 cases with special emphasis of abscesses and neurological complications. Clin Orthop Rel Res 1990; 257: 67-78
Rezai Ali R. Et al. Modern management of spinal tuberculosis. Neurosurgery. January 1995; 36 (1): 87-96.
Vidyasagar CO et al. Management of tuberculosis of the spine (spinal:) neurological complications. Ann R Coll Surg Engl 1990; 76: 80-89.
Oheneba Boachie – adjei MD, Robert G, Squillante MD. Tuberculosis of the spine. Orthop Clin North Am 1996; 27 (1): 95-102.
Pott P. Remarks on the that kin of the lower limbs which is frequently found to accompany curvature of the spine and is supposed to be caused by it. Together with its method of cure, to which are added, observations on the necessity and property of amputation in certain circumstances. Medical Classic 1936; 1: 271-323.
Denis F. The three columm spine and its significance in the classification of acute/toracolumbar spinal injuries. Spine 1983; 8: 817-831.
Medical Research Council Working Party of tuberculosis of the spine. 1 year assessment of controlled trial comparing debridement and anterior spinal fusion in the management of tuberculosis of the spine in patients on standard chemotherapy in Hong Kong. J Bone Joint Sur Br. 1982; 64B (4): 393-397.
Upadhays SS et al. The effect of age on the change in deformity after radical resection and anterior arthrodesis for tuberculosis of the spine. J Bone Joint Sur 1994; 76ª (5) May:701-708.
Upadhays SS et al. Longitudinal changer in spinal deformity after anterior spinal surgery for tuberculosis of the spine in adults. Spine 1994; 19: 542-549.
Goel MK. Treatment of Pott’s paraplegia by operation. J. Bone Joint Surg 1967; 49B: 674-681.
Blancarte BL. Manual de técnicas y procedimientos de laboratorio de tuberculosis. INDRE México SSA;1992.
Elisa Smigh, M, Andersen A. Mc Carthy EG, Rodha M, Schutte H. The micobacterium tuberculosis 38-KD antigen overproduction in Escherichia coli. Purification and characteristic gene. 1992; 117: 53-60.
Thanes MD. Immunochromatographic antibody and antigen detection for the immunodiagnosis of tuberculosis; why not? What more is needed?, Where do we stand today? J Infect Dis. 1988; 158: 4:680-680.
PCR-ANNE Brisson-Noel, Diagnosis of tuberculosis by DNA amplification in clinical practice involution. Lancet 1991 (August 10); 338: 364-366.
Nunbaing MD. Enc S, Spinal tuberculosis: a diagnostic and management challenge. J. Neunime 1995: 83; 243-247.
Rajemain R. Balasubramanian, R, Venkatesan P. Short-course chemotherapy in the treatment of Pott’s paraplegia: report on five year Follow-up. Int J Tuber Lung Dis 1997: 1(2): 152-158.
De La Torre GD, Lima Flores R. Sistema de instrumentación transpedicular modificado para el tratamiento de la inestabilidad vertebral toracolumbar. Rev Cir Cir 1999: 67; 102-107.
20. Capenen N. The evaluation of lateral rachiotomy. J Bone Joint Surg 1954: 84B: 173-179.
Alexander GL. Neurological complications of spinal tuberculosis. Proceedings of the Royal Society of Medicine. Proc Royal Soc Med 1946; 39: 730.
Hodgson AR, Stock FE. Preliminary communication on the radical treatment of Pott’s disease and Pott’s paraplegia. Bri J Surg 1956; 44: 266.