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2012, Number 1

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Enf Infec Microbiol 2012; 32 (1)

Methicillin-resistant Staphylococcus aureus (MRSA) in a pediatric hospital, urban and rural community

Villaseñor MR, Farías FG, Carrillo MME, Jáuregui LJJ, Castañeda RFE, Lepe CBE, Martínez RR, Villaseñor SA

Language: Spanish
References: 31
Page: 6-10
PDF size: 100.14 Kb.


ABSTRACT

Background. The prevalence of Methicillin-Resistant Staphylococcus aureus (MRSA) in hospitals and in nasal carriers of urban and rural communities is variable, reason why local information is crucial for a proper patient management.
Material and methods. A transversal comparative study, from August 2009 to February 2011, was made. From a Children´s Hospital were isolated 169 MRSA (monthly prevalence ranged 5-76%) and 314 Methicillin-Sensitive Staphylococcus aureus (MSSA). In ambulatory people of urban zone: Cultures from nostrils of 219 nursery students and their familiars, and 40 pre-surgical children at hospital admission were included, from the rural zone: 286 patients with no infectious problems, attending primary care settings were also cultured. Nostrils cultures were performed and plated on selective medium, and S. aureus identified by standard techniques. Susceptibility to cefoxitin (FOX), erythromycin (E), rifampim (RA), clindamycin (CC), trimethoprim-sulfamethoxazole (SXT) was performed by Kirby-Bauer method according to CLSI 2010. D-test was performed.
Results. From the Children´s Hospital were studied 69 strains, 67 MRSA and 2 MSSA. From urban zone: we isolated 42 (16%) S. aureus strains; 5 (12%) MRSA and 37 MSSA, from rural zone: we isolated 24 (8%) S. aureus strains; 1 (4%) MRSA and 23 MSSA. Resistance of all MRSA strains to E, RA, CC y SXT was 96, 0, 89 y 0% respectively; of MSSA strains resistance was 15, 0, 0 y 0% respectively. In strains from urban zone, D test was positive in 13% of the MSSA.
Conclusions. The prevalence of MRSA in the Children´s Hospital was similar to other reports worldwide. Prevalence of nasal carriers from urban and rural zone was lower than other reports.


REFERENCES

  1. Bode LG, Kluytmans JA, Wertheim HF, Bogaers D, Vandenbroucke-Grauls CM, Roosendaal R et al. “Preventing surgical-site infections in nasal carriers of Staphylococcus aureus”. N Engl J Med 2010; 362: 9-17.

  2. Nouwen J, Schouten J, Schneebergen P, Snijders S, Maaskant J, Koolen M et al. “Staphylococcus aureus carriage patterns and the risk of infections associated with continuous peritoneal dialysis”. J Clin Microbiol 2006; 44: 2233-2236.

  3. Waldvogel FA. “Staphylococcus aureus”. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and Practice of Infectious Diseases, Philadelphia: Churchill Livingstone; 2000, p. 2513-2536.

  4. Deleo FR, Otto M, Kreiswirth BN, Chambers HF. “Community-associated meticillin-resistant Staphylococcus aureus”. Lancet 2010; 375: 1557-1568.

  5. Lebon A, Labout JA, Verbrugh HA, Jaddoe VW, Hofman A, van Wamel WJ et al. “Role of Staphylococcus aureus nasal colonization in atopic dermatitis in infants: the Generation R Study”. Arch Pediatr Adolesc Med 2009; 163: 745-749.

  6. Gonzalez BE, Martinez-Aguilar G, Hulten KG, Hammerman WA, Coss-Bu J, Avalos-Mishaan A et al. “Severe Staphylococcal sepsis in adolescents in the era of community-acquired methicillin-resistant Staphylococcus aureus”. Pediatrics 2005; 115: 642-648.

  7. Lim HS, Lee H, Roh KH, Yum JH, Yong D, Lee K et al. “Prevalence of inducible clindamycin resistance in staphylococcal isolates at a Korean tertiary care hospital”. Yonsei Med J 2006; 47: 480-484.

  8. Luciani K, Nieto-Guevara J, Saez-Llorens X, de SO, Morales D, Cisternas O et al. “Methicillin-resistant Staphylococcus aureus disease in Panama”. An Pediatr (Barc ) 2011.

  9. Anwar MS, Jaffery G, Rehman Bhatti KU, Tayyib M, Bokhari SR. “Staphylococcus aureus and MRSA nasal carriage in general population”. J Coll Physicians Surg Pak 2004; 14: 661-664.

  10. Robicsek A, Suseno M, Beaumont JL, Thomson RB, Jr., Peterson LR. “Prediction of methicillin-resistant Staphylococcus aureus involvement in disease sites by concomitant nasal sampling”. J Clin Microbiol 2008; 46: 588-592.

  11. Uneke CJ, Ogbonna A, Oyibo PG, Onu CM. “Bacterial contamination of stethoscopes used by health workers: public health implications”. J Infect Dev Ctries 2010; 4: 436-441.

  12. Hewlett AL, Falk PS, Hughes KS, Mayhall CG. “Epidemiology of methicillin-susceptible Staphylococcus aureus in a university medical center day care facility”. Pediatr Infect Dis J 2010; 29: 145-147.

  13. Lucet JC, Paoletti X, Demontpion C, Degrave M, Vanjak D, Vincent C et al. “Carriage of methicillin-resistant Staphylococcus aureus in home care settings: prevalence, duration, and transmission to household members”. Arch Intern Med 2009; 169: 1372-1378.

  14. Johansson PJ, Gustafsson EB, Ringberg H. “High prevalence of MRSA in household contacts”. Scand J Infect Dis 2007; 39: 764-768.

  15. Pai V, Rao VI, Rao SP. “Prevalence and Antimicrobial Susceptibility Pattern of Methicillin-resistant Staphylococcus Aureus [MRSA] Isolates at a Tertiary Care Hospital in Mangalore, South India”. J Lab Physicians 2010; 2: 82-84.

  16. Asghar AH, Momenah AM. “Methicillin resistance among Staphylococcus aureus isolates from Saudi hospitals”. Med Princ Pract 2006; 15: 52-55.

  17. Akpaka PE, Kissoon S, Swanston WH, Monteil M. “Prevalence and antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus isolates from Trinidad & Tobago”. Ann Clin Microbiol Antimicrob 2006; 5: 16.

  18. Alvarez JA, Ramirez AJ, Mojica-Larrea M, Huerta JR, Guerrero JD, Rolon AL et al. “Methicillin-resistant Staphylococcus aureus at a general hospital: epidemiological overview between 2000-2007”. Rev Invest Clin 2009; 61: 98-103.

  19. Klevens RM, Edwards JR, Tenover FC, McDonald LC, Horan T, Gaynes R. “Changes in the epidemiology of methicillin-resistant Staphylococcus aureus in intensive care units in US hospitals, 1992-2003”. Clin Infect Dis 2006; 42: 389-391.

  20. Price CS, Williams A, Philips G, Dayton M, Smith W, Morgan S. “Staphylococcus aureus nasal colonization in preoperative orthopaedic outpatients”. Clin Orthop Relat Res 2008; 466: 2842-2847.

  21. Haley CC, Mittal D, Laviolette A, Jannapureddy S, Parvez N, Haley RW. “Methicillin-resistant Staphylococcus aureus infection or colonization present at hospital admission: multivariable risk factor screening to increase efficiency of surveillance culturing”. J Clin Microbiol 2007; 45: 3031-3038.

  22. Torano G, Quinones D, Hernandez I, Hernandez T, Tamargo I, Borroto S. “Nasal carriers of methicillin-resistant Staphylococcus aureus among cuban children attending day-care centers”. Enferm Infecc Microbiol Clin 2001; 19: 367-370.

  23. Creech CB, Kernodle DS, Alsentzer A, Wilson C, Edwards KM. “Increasing rates of nasal carriage of methicillin-resistant Staphylococcus aureus in healthy children”. Pediatr Infect Dis J 2005; 24: 617-621.

  24. Castro-Orozco R, Villafane-Ferrer LM, Alvarez-Rivera E, De Arco MM, Rambaut-Donado CL, Vitola-Heins GV. “Methicillin-resistant Staphylococcus aureus in children attending school in Cartagena, Colombia”. Rev Salud Publica (Bogota ) 2010; 12: 454-463.

  25. Lo WT, Wang CC, Lin WJ, Wang SR, Teng CS, Huang CF et al. “Changes in the nasal colonization with methicillin- resistant Staphylococcus aureus in children: 2004-2009”. PLoS One 2010; 5: e15791.

  26. Rijal KR, Pahari N, Shrestha BK, Nepal AK, Paudel B, Mahato P et al. “Prevalence of methicillin resistant Staphylococcus aureus in school children of Pokhara”. Nepal Med Coll J 2008; 10: 192-195.

  27. Shopsin B, Mathema B, Martinez J, Ha E, Campo ML, Fierman A et al. “Prevalence of methicillin-resistant and methicillin-susceptible Staphylococcus aureus in the community”. J Infect Dis 2000; 182: 359-362.

  28. Lamaro-Cardoso J, de LH, Kipnis A, Pimenta FC, Oliveira LS, Oliveira RM et al. “Molecular epidemiology and risk factors for nasal carriage of staphylococcus aureus and methicillin-resistant S. aureus in infants attending day care centers in Brazil”. J Clin Microbiol 2009; 47: 3991-3997.

  29. Chatterjee SS, Ray P, Aggarwal A, Das A, Sharma M. “A community-based study on nasal carriage of Staphylococcus aureus”. Indian J Med Res 2009; 130: 742-748.

  30. Pathak A, Marothi Y, Iyer RV, Singh B, Sharma M, Eriksson B et al. “Nasal carriage and antimicrobial susceptibility of Staphylococcus aureus in healthy preschool children in Ujjain, India”. BMC Pediatr 2010; 10: 100.

  31. Tang CS, Wang CC, Huang CF, Chen SJ, Tseng MH, Lo WT. “Antimicrobial susceptibility of Staphylococcus aureus in children with atopic dermatitis”. Pediatr Int 2010.




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