Orozco-Gómez LP, Zavaleta-Herrera FE, Casaroli-Marano RP

Language: Spanish
References: 18
Page: 188-192
PDF size: 95.95 Kb.

ABSTRACT

We have studied 14 eyes with diagnosis of keratopathy, all after penetrating keratoplasty during 5 years. We have registrated visual capacity, characteristics of graft, and changes through the years. We have found a direct relationship (p = 0.0004) between initial changes of corneal disease and the evolution of the graft, showing the different stages of opacity and return of the disease. We have demonstrated best visual results in patients with penetrating keratoplasty using donor grafts of 7.5 mm diameter or less (p = 0.02). With histopathologic studies of the primary cornea, we could demonstrate the following changes: Corneal elastotic degeneration including stromal deposits (93%); changes in Bowman’s layer (85%); stromal scars (85%), and alterations in epithelium (65%). Chronic evolution of the disease, inflammation of conjunctiva, and very characteristic geographic distribution truly relevant to these patients.

REFERENCES

1. Gray RH, Johnson GJ, Freedman A. Climatic droplet keratopathy. Surv Ophthalmol 1992; 36; 241.

2. Grayson M. Involutional changes and degenerations. In: Grayson M. editor. Diseases of the cornea. 2nd ed. St. Louis, MO, USA: 1983. p. 212-215, 227.

3. Waring GO III. Corneal degenerations.In: Leibowitz, HM, editor. Corneal disorders clinical diagnosis and management. Philadelphia, PA, USA: Saunders; 1998. p. 314-318.

4. Dolin PJ, Johnson GJ. Solar ultraviolet radiation and ocular disease: a review of the epidemiological and experimental evidence. Ophthalmic Epidemiol 1994; 1: 155.

5. Garner A, Morgan G, Tripathi R. Climatic droplet keratopathy (keratinoid degeneration). Pathologic findings. Arch Ophthalmol 1973; 89: 198.

6. Bownstein S, Rodríguez MM, Albert EN. The elastotic nature of hyaline corneal deposits. A histochemical, fluorescent, and electron microscopic examination. Am J Ophthalmol 1973; 75: 799.

7. Kamocki V. Weitere Patholgischanatomische beitrage zur kenntniss diabetischer augenerkrankungen. Arch Angenheilk 1892; 25: 209.

8. Baquis E. Die colloïde degeneration der cornea, ein beitrag zur kenntniss der entstehung des colloïds aus epitheliales elementen. Graefe’s Arch Clin Exp Ophthalmol 1898; 46: 553.

9. Von Recklinghausen FO. Handbuch der allgemeines pathologie des kreislaufs und der Ernährung. In: Deutsche chirurgie, lieferung 2/3. Stuttgart, Germany: Enke; 1883.

10. Luigli L. Degeneratio corneae sphaerularis elaioides. Graefe’s Arch Clin Exp Ophthalmol 1935: 134: 211.

11. Bietti GB. Acta XIX Concillium Ophthalmologicum. Bombay, India: 1962; 1: 421.

12. Volpi U, Serra A. Contributo alla conoscenza della degenerazione sferulae elaioidea della cornea. Ann Oftal Clin Ocul 1967; 93: 1305.

13. Duke-Elder S, Leigh AG. Diseases of the outer eye. Part 2. Cornea and sclera. In: Duke-Elder S, editor. System of ophthalmology. Vol. VIII. St. Louis, MO, USA: Mosby Co; 1965. p. 873-888.

14. Freedman A. Labrador keratopathy. Arch Ophthalmol 1965; 74: 198.

15. Freedman A. Climatic droplet keratopathy (keratinoid degeneration) Clinical aspects. Arch Ophthalmol 1973; 89: 193.

16. Fraunfelder FT, Hanna C. Spheroidal degeneration of cornea and conjunctiva, 3 incidences, classification, and etiology. Am J Ophthalmol 1973; 76: 41.

17. Johnson GJ, Ghosh M. Labrador keratopathy: clinical and pathological findings. Can J Ophthalmol 1975; 10: 119.

18. Barraquer J, Rutllan J. Atlas de microcirugía de la córnea. Barcelona, Spain: Scriba, S.A.; 1998. p. 237-273.