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Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2012, Number 1

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Rev Mex Patol Clin Med Lab 2012; 59 (1)

Alterations in the vaginal pH associated to lactobacilli or Döderlein’s bacillus

Sánchez-Hernández JA, Mayta-Baldivieso MJ, Rivera-Tapia JA

Language: Spanish
References: 22
Page: 56-60
PDF size: 56.02 Kb.


ABSTRACT

The vaginal microflora, is protected against pathogens by Döderlein bacillus, Lactobacillus acidophilus and Lactobacillus vaginalis, through three complementary mechanisms: a) specific adherence to the epithelium, b) the production of antimicrobial compounds and c) the coaggregation with pathogens, which enhances its effect microbiocide. In order to maintain the vaginal pH, improved debugging and intravaginal turn prevent the development of pathogens such as Gardnerella vaginalis and Neisseria gonorrhoeae. However, the literature describes cases of women with excessive increase in Lactobacillus, known as lactobacilosis, a situation that causes extreme acidification of the vaginal environment, resulting in lysis of the epithelial cells which is called cytolytic vaginosis. To support studies showing that high amounts of lactobacilli Bacillus Döderlein or cause changes in vaginal pH can cause extreme acidification. Based on the foregoing, we conducted a retrospective, transversal vaginal specimens from 197 women who attended the Laboratorio de Biología Celular de la Facultad de Medicina de la Benemérita Universidad Autónoma de Puebla, México from 2009 to 2010. Of the 197 women, Women in itself Detect to 62 (31.47%) of lactobacilli with which The 28 women (45.16%) had extreme vaginal pH acidification Increased amounts Döderlein for Bacillus or Lactobacillus. The higher is the number of bacilli or lactobacilli Mayor Döderlein cause an alteration in vaginal pH may cause acidification every time a more extreme, case of no early treatment mower without provocation or lactobacilosis cytolytic vaginosis.


REFERENCES

  1. Fernández-Cid A, Fernández-Cid M. El pH vaginal y su importancia clínica. Ginecol Obstet Clin 2004; 5: 75-80.

  2. Valore EV, Wiley DJ, Ganz T. Reversible deficiency of antimicrobial polypeptides in bacterial vaginosis. Infect Immun 2006; 74: 5693–5702.

  3. Alvarez-Olmos MI, Barousse MM, Rajan L, Van Der Pol BJ, Fortenberry D, Orr D, Fidel PL Jr. Vaginal Lactobacilli in adolecents. Sex Transm Dis 2004; 31: 393-400.

  4. Marelli G, Papaleo E, Ferrari A. Lactobacilli for prevention of urogenital infections: A review. Eur Rev Med Phannacol Sci 2004; 8: 87-95.

  5. Agnew KJ, Hillier SL. The effect of treatment regimens for vaginitis and cervicitis on vaginal colonization by Lactobacilli. Sex Transm Dis 1995; 22: 269-273.

  6. De Backer E, Verhelst R, Verstraelen H, Alqumber HA, Burton JP, Tagg JR, Temmerman M, Vaneechoutte M. Qualitative determination by real-time PCR of four vaginal Lactobacillus species, Gardnerella vaginalis and Atopobium vaginae indicates an inverse relationship between L. Gasseri and L. Iners. BMC Microbiol 2007; 7: 115.

  7. Dong-hui Y, Zhi LU and Jian-rong SU. Comparison of main lactobacillus species between healthy women and women with bacterial vaginosis. Chin Med J 2009; 122: 2748-2751.

  8. Anukam KC, Osazuwa EO, Ahonkhai I, Reid G. Lactobacillus vaginal Microbiota of women attending a Reproductive health care service in Benin city, Nigeria. Sex Transm Dis 2006; 33: 59-62.

  9. Wilks M, Wiggins R, Whiley A, Hennessy E, Warwick S, Porter H, Corfield A, Millar M. Identification and H2O2 production of vaginal lactobacilli from pregnant women at high risk of preterm birth and relation with outcome. J Clin Microbiol 2004; 42: 713-717.

  10. Juárez Tomás MS, Ocaña VS, Wiese B, Nader-Macías ME. Growth and lactic acid production by vaginal Lactobacillius acidophillus CRL 1259, and inhibition of uropathogenic Escherichia coli. J Med Microbiol 2003; 52: 1117-1124.

  11. Polatti F, Rampino M, Magnani P, Mascarucci P. Vaginal pH- lowering effect of locally applied vitamin C in subjects with high vaginal Ph. Gynecol Endocrinol 2006; 22: 230-234.

  12. Tamrakar R, Yamada T, Furuta I, Cho K, Morikawa M, Yamada H, Sakuragi N, Minakami H. Association between lactobacillus species and bacterial vaginosis-related bacteria, and bacterial vaginosis scores in pregnant Japanese women. BMC Infect Dis 2007; 7:128.

  13. Morris M, Nicoll A, Simms I, Wilson J, Catchpole M. Bacterial vaginosis: A public health review. BJOG 2001; 108: 439-450.

  14. Martín R, Soberón N, Vázquez-Camino F. La microbiota vaginal: Composición, papel protector, patología asociada y perspectivas terapéuticas. Enferm Infecc Microbiol Clin 2008; 26: 160-167.

  15. Martín R, Suárez JE. Biosynthesis and degradation of H2O2 by vaginal lactobacilli. Appl Environ Microbiol 2010; 76: 400-405.

  16. Lepargneur JP, Rousseau V. Role protecteur de la flore de Doderlein. J Gynecol Obstet Biol Reprod 2002; 31: 485-494.

  17. Ricci AP, Contreras ML, Contreras SL. Vaginosis citolítica: Un diagnóstico diferencial poco frecuente de vulvovaginitis micótica a repetición. Rev Chil Obstet Ginecol 2010; 10: 194-198.

  18. Cerikcioglu N, Beksac MS. Cytolytic vaginosis: Misdiagnosed as candidal vaginitis. Infect Dis Obstet Gynecol 2004; 12: 13-16.

  19. Wathne B, Holst E, Hovelius B, Mårdh PA. Vaginal discharge-comparison of clinical, laboratory and microbiological findings. Acta Obstet Gynecol Scand 1994; 73:802-808.

  20. 20.Demirezen S. Cytolytic vaginosis: examination of 2947 vaginal smears. Eur J Public Health 2003; 11: 23-24.

  21. Amaral R, Giraldo PC, Gonçalves AK, Junior JE, Santos- Pereira S, Linhares I. Evaluation of hygienic douching on the vaginal microflora of female sex workers. Int J STD AIDS 2007; 18: 770-773.

  22. Secor RM. Cytolytic vaginosis: a common cause of cyclic vulvovaginitis. Nurse Pract Forum 1992; 3: 145-148.




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