2012, Number 1
Effectiveness of the meningococcal B-C vaccine in the vaccinated children population from 1996 to 2009 in Ciego de Avila
Language: Spanish
References: 10
Page:
PDF size: 55.06 Kb.
ABSTRACT
A retrospective, observational and cohort investigation was carried out during 14 years to determine the effectiveness of the meningococcal B-C vaccine applied in the vaccinated and not vaccinated cohort from 1996 to 2009. The study universe was represented by the total of vaccinated and not vaccinated live births from 1996 to 2009 constituted in two cohorts of vaccinated and not vaccinated with the meningococcal B-C vaccine and that were followed until they were 10 years. The information compilation technique was by means of compulsory declared cards and clinical records of notified cases, looking for the vaccination antecedents. The results were represented in tables and the information was analyzed determining the effectiveness by vacunal cover, relative risk and population preventable fraction. The main results were: the risk of becoming ill in the cohorts population of vaccinated and not vaccinated during the study period is very low and the Cuban vaccine VA-MENGOC-BC reaches a high protection in the childhood. Only the group of 5 to 9 years shows the high-risk value although with magnitude of protection.REFERENCES
Delgado Ross F, Rubio Rodríguez A, Hernández Pupo A. Morbimortalidad por meningoencefalitis bacteriana, Hospital General Docente “Vladimir Ilich Lenin”, Holguín, 2000- 2004. Correo Cient Med Holguín [Internet]. 2006 [citado 10 Jul 2010]; 10(1): 21-30. Disponible en: http://www.cocmed.sld.cu/no101/n101ori6.htm
Sierra VG, Campa C, Valcárcel M, Sotolongo F, Figueredo L. Efficacy evaluation of the Cuban vaccine VA-MENGOC-BC against disease caused by serogrupo B Neisseria meningitidis. En: Markachtman C, et al., editors. Neisseriae 1990. Proceedings of the Seventh International Conference on Pathogen Neisserias; 1990 Sept. 9-14; Berlin, Federal Republic of Germany. Berlín: Walter Dgruyter, 1991:129.
Dickinson Meneses FO, Pérez Rodríguez AE. Las meningoencefalitis bacterianas en la población infantil cubana: 1998-2000. Rev Cubana Pediatr [Internet]. 2002 [citado 10 Jul 2010]; 74(2): 106-114. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75312002000200002&lng=es&nrm=iso