2005, Number 3
Enfermedad de Creutzfeldt Jakob asociada a tiroiditis autoinmune: Reporte de un caso
Salas PG, Zavala RA, Aguilar NS, Gamiz MAL, Horta MSG, Vargas VE, López RL, De la Sancha MLM
Language: Spanish
References: 6
Page: 59-67
PDF size: 619.77 Kb.
ABSTRACT
This is the case of a 70 year old male, with history of impair gait, auditory hallucinations, hypoacusis, diplopia, ptosis, dementia, and cerebellar syndrome for 6 months. The laboratory findings were, leukocytosis, increased hepatic enzymes, hypertonic hypovolemic hypernatremia, hypoalbuminemia, leukocyturia, bacteriuria, proteinuria, hyperglycorrhachia, progressive hypoxemia, and mixed acidosis. The antibodies anti-thyroglobulin and anti-peroxidase were high, also the protein 14-3-3. The diagnosis of encephalopathy spongiform and thyroiditis was made. He was treated with steroids, antibiotics, plasmapheresis and immunoglobulins. He evolved with a progressive neurologic deterioration and sepsis, dying after this. The diagnosis was corroborated by an autopsy, concluding with the diagnosis of Creutzfeldt-Jakob a sporadic variety and Autoimmune Thyroiditis.REFERENCES