2010, Number 09-10
<< Back Next >>
Medicina & Laboratorio 2010; 16 (09-10)
Enfermedades difusas del hígado: evaluación con resonancia magnética
Pulgarín RLG, Rascovsky RS, Delgado BJA, Llano SJF, Vélez AJM, JSanz RJA, Calvo BVD
Language: Spanish
References: 23
Page: 459-468
PDF size: 506.67 Kb.
ABSTRACT
Introduction: Until the end of the 20th century, diffuse liver disease was a difficult diagnosis through imaging methods and its confirmation was only possible with liver biopsy and its histopathologic result. Currently, advanced MRI techniques can make possible a more reliable diagnosis of these diseases with a non-invasive technique, compared to other imaging methods and diagnostic modalities.
Objective: To describe the magnetic resonance imaging (MRI) findings of various diffuse liver diseases.
Methods: A descriptive case series was performed with patients with diffuse liver disease who attended a health care institution specialized in MRI services.
Results: There were four cases with cirrhosis of different etiologies: one caused by hepatitis B and hepatocellular carcinoma, and with an associated diffuse malignant thrombosis of the portal vein, another caused by hepatitis C, the third of vascular origin (congestive), and a case of alcoholic cirrhosis. Similarly two other cases were evaluated for steatosis, one with a focal non-infiltrative area and one with generalized fatty liver infiltration. In addition, a secondary hemochromatosis case was analyzed.
Conclusion: MRI becomes a non-invasive diagnostic tool that does not involve exposure to ionizing radiation, useful for preoperative evaluation and monitoring of diffuse liver diseases, regardless of its etiology.
REFERENCES
Dancygier H. Clinical Hepatology: Principles and Practice of Hepatobiliary Diseases. Volume 2. Berlin: Springer; 2010.
Braga L, Semelka RC, Armao D. Liver. In: Semelka RC, editor. Abdominal-Pelvic MRI. 2nd ed. Hoboken: John Wiley and sons Inc; 2006. p. 47–445.
Anthony PP, Ishak KG, Nayak NC, Poulsen HE, Scheuer PJ, Sobin LH. The morphology of cirrhosis: definition, nomenclature, and classification. Bull World Health Organ 1977; 55: 521-540.
Valls C, Iannacconne R, Alba E, Murakami T, Hori M, Passariello R, et al. Fat in the liver: diagnosis and characterization. Eur Radiol 2006; 16: 2292–2308.
Stark D. Hepatic iron overload: paramagnetic pathology. Radiology 1991; 179: 333-335.
Bonkovsky H, Rubin R, Cable E, et al. Hepatic iron concentracion: noninvasive estimation by means of MR imaging techniques. Radiology 1999; 212: 227-234.
Danrad R, Martin DR. MR imaging of diffuse liver diseases. Magn Reson Imaging Clin N Am 2005; 13: 277–293.
Low RN. Abdominal MRI advances in the detection of liver tumours and char- acterisation. Lancet Oncol 2007; 8: 525–535.
Taouli B, Ehman RL, Reeder SB. Advanced MRI methods for assessment of chronic liver disease. Am J Roentgenol 2009; 193: 14–27.
Chandarana H, Taouli B. Diffusion and perfusion imaging of the liver. Eur J Radiol (2010), doi:10.1016/j.ejrad.2010.03.016
Ros PR, Mortele KJ. Diffuse liver disease. Clin Liver Dis 2002; 6: 181-201.
Balci1 NC, Befeler AS, Leiva P, Pilgram TK, Havlioglu N. Imaging of liver disease: Comparison between quadruple-phase multidetector computed tomography and magnetic resonance imaging. J Gastroenterol Hepatol 2008; 23: 1529-1527.
Boll DT, Merkle EM. Diffuse Liver Disease: Strategies for Hepatic CT and MR Imaging Radiographics 2009; 29: 1591-1614.
Semelka RC, Martin DR, Balci C, Lance T. Focal liver lesions: comparison of dual-phase CT and multisequence multiplanar MR imaging including dynamic gadolinium enhancement. J. Magn. Reson Imaging 2001; 13: 397–401.
Noone TC, Semelka RC, Chaney DM, Reinhold C. Abdominal imaging studies: comparison of diagnostic accuracies resulting from ultrasound, computed tomography, and magnetic resonance imaging in the same individual. Magn. Reson Imaging 2004; 22: 19–24.
Kamel IR, Liapi E, Fishman EK. Liver and biliary system: evaluation by multidetector CT. Radiol Clin North Am 2005; 43: 977–997.
Oto A, Tamm EP, Szklaruk J. Multidetector row CT of the liver. Radiol Clin North Am 2005; 43: 827–848.
Winterer JT, Kotter E, Ghanem N, Langer M. Detection and characterization of benign focal liver lesions with multislice CT. Eur Radiol 2006; 16: 2427–2443.
Semelka RC, Armao DM, Elias J Jr, Huda W. Imaging strategies to reduce the risk of radiation in CT studies, including selective substitution with MRI. J Magn Reson Imaging 2007; 25: 900–909.
Danet IM, Semelka RC, Braga L. MR imaging of diffuse liver disease. Radiol Clin North Am 2003; 41: 67-87.
Martin D, Danrad R, Hussain S. MR imaging of the liver. Radiol Clin N Am 2005; 43: 861-886.
Danrad R, Martin DR. MR imaging of diffuse liver diseases. Magn Reson Imaging Clin N Am 2005; 13: 277–293.
Semelka RC, Martin DR, Balci NC. Magnetic resonance imaging of the liver: how I do it. J Gastroenterol Hepatol 2006; 21: 632–637.