2005, Number 1
Rev Esp Med Quir 2005; 10 (1)
Biopsia guiada por referencias anatómicas en un paciente con Leucoencefalopatía Mutifocal Progresiva (LMP)
Maciel R, Baltazar J, García S, González A, Hernández M, Zarate MA, Félix I
Language: Spanish
References: 11
Page: 74-78
PDF size: 146.19 Kb.
ABSTRACT
The object of this case is to present a technique for a cerebral biopsy guided by the distance of an establish anatomical reference point, avoiding the use of a stereotaxic system and with low risk for a patient with neurological deterioration without a definitive diagnosis.The case is of a 34 year old woman with a quickly progressive neurological disease and clinical evidence of disseminated brain affection. She was studied by no risky methods and some therapeutic measures were used, without any positive result, so we decided to perform a cerebral biopsy with a technique guided by the measure of anatomical references, this way took sufficient brain tissue for the histopathologic diagnosis with minimum risk for the patient. The histopathologic study reported a Progressive Multifocal Leucoencephalopathy (PML), the clinical relevance, is that the patient didn’t show any immunodeficiency signs.
REFERENCES
Beck RC, Kohn DJ, Tuohy MJ. Detection of polyoma virus in brain tissue of patients with progressive multifocal leu- Figura 5: Proliferación de oligodendrocitos con cuerpos de inclusión intracitoplasmáticos [flechas negras]. Destrezas clínicas koencephalopathy by real-time PCR and pyrosequencing. Diagnostic Molecular Pathology. 2004 13(1):15-21