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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2011, Number 1

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Bol Clin Hosp Infant Edo Son 2011; 28 (1)

Whooping Cough and Coqueluchiod Syndrome in Children Under One Year Old: Mortality Associated Risk Factors

Gómez-Rivera N, García-Zarate MG, Álvarez-Hernández G, Villalobos-García L, Fonseca-Chon I, Cano-Rangel MA, Vázquez-Pizaña E, López-Miranda A

Language: Spanish
References: 24
Page: 2-6
PDF size: 105.88 Kb.


ABSTRACT

Objective: To describe the clinical presentation of 48 cases and the risk factors associated with mortality.
Study Design: Transversal, descriptive, between January 2009 and March 2010.
Materials y Methods: Two groups were compared for the descriptive analysis: group 1; patients who passed away, group 2, patients who survived. The selected variables were: Age, sex, cough characteristics, vaccination history, leukocytosis, X-ray, antimicrobial treatment and mortality. The statistic significance was evaluated by Student T test, Pearson 2 test and Fisher´s Exact Test. Results of p ‹.05 were considered significant.
Results: Positive samples to patients in 18 cases (38%), positive samples to relatives in 5 cases (10%). Positive samples group 1; 7 cases (100%), positive samples group 2, 11 cases (61%). Apneas: group 1; 7 cases, group 2: 5 cases; 42% when p = 0.001 (significant). Pneumonias: group 1; 7 cases, group 2; 25 cases, when p= 0.0001 (significant). Starting leucocytes (average) group1; 74,457 mm3. Group 2 51,667 mm3, p = 0.0177. Leukocytosis on day 4; group 1 80,014. Group 2 20,428 mm3, when p = 0.0001. Mortality 15%.
Conclusions: Presence of apnea, leukocytosis and pneumonia can be considered as a risk factor considering they were significantly higher in G1 in comparison to G2.


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