2011, Number 598
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Rev Med Cos Cen 2011; 68 (598)
β-Talasemia
Vargas MC
Language: Spanish
References: 10
Page: 355-357
PDF size: 255.54 Kb.
ABSTRACT
β thalassemia consist in mutations that lead to defective synthesis of beta chains of hemoglobin, thus, are other types of hemoglobin in greater numbers, while producing excessive free alpha chains, also depending on how important is the deficit and the degree or severity of the disease, bringing the clinical and laboratory findings vary, as thalassemia minor, intermedia or major.
REFERENCES
Harrison. Principios de Medicina Interna. In: Benz E. 16a edición: McGraw Hill Company, 2005: 671-674.
Lay S. Pathophysiology of β Thalassemia - A Guide to Molecular Therapies. American Society of Hematology. 2005, 31-37.
Malik P, Arumugam P. Gene Therapy for β-Thalassemia. American Society of He-matology. 2005, 45-50.
Mayayo M, Anguita J, Pérez I, Pintado T. Anemia ferropénica: etiopatogenia, cri-terios diagnósticos, tratamiento, preparados farmacológicos de hierro. Medicine. 2001, 8: 2676-2683.
Montejano L, Gilsanz F. El síndrome anémico: concepto, manifestaciones clínicas, clasificación y criterios diag-nósticos. Medicine 2001, 8: 2621-2624.
Muñoz I, Bastos M, López A, Hernández F. Protocolo diagnóstico de las anemias microcíticas. Medicine. 2008, 10:1363-1365.
Pastor I, Roa S, Rodríguez R, González R. Bases genéticas de las enfermedades hereditarias. Medicine 2002, 8: 4414-4421.
Rodríguez W, Saénz G. Hematología analítica Tomo 1. EDNASSS. 2008: 221-237.
Rund D, Rachmilewitz E. β –Thalas-semia. The new england journal of medi-cine. 2005, 353: 1135-1146.
Vives J.L. Anemias por defectos Congénitos de la hemoglobina: hemoglobinopatías estructurales y talasemias. Medi-cine. 2001; 8: 2684-2693.