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ISSN 1405-1699 (Print)
Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2010, Number 3

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Alerg Asma Inmunol Pediatr 2010; 19 (3)

Relative power of allergenic extracts from different sources on patients with asthma an allergic rhinitis

Abou-Khair F, Rodríguez-Santos O, Labrada-Rosado A, Celio MR, Meli VR, Barata HJ

Language: Spanish
References: 14
Page: 81-85
PDF size: 60.35 Kb.


ABSTRACT

Background: Skin tests require extracts with high quality, which can be measured by determining their allergenic potence by using different concentrations of extracts from a manufacturer or comparing extracts from different manufacturers. Objective: To compare dust mite extracts produced by manufacturers from Spain, Argentina and Cuba by using the skin response to the Prick Test. Materials and methods: The Prick Test was performed on 26 patients aged 2 to 15 years with asthma and rhinitis at the clinic Previsora, Camaguey, Cuba, with extracts of Dermatophagoides pteronyssinus (Dp), Dermatophagoides farinae (Df), Dermatophagoides siboney (Ds) and Blomia tropicalis produced by DIATER (Argentina), ALK- Abelló (Spain) y BIO-CEN (Cuba). The statistical analysis was carried out with Microsoft Excel. Results: Among the patients, 84.6% attributed the symptoms to changes in weather and house dust. The diameter of the wheal was greater for ALK- Abelló, but no statistical significance was found (p › 0.05). The relationship between wheal diameter and allergen concentrarion with BIOCEN showed a linear correlation between average diameter and log of the concentration in the range of 4,000 to 100,000 UB/mL. Prick tests with diameters ≥ 3 mm showed a greater proportion for ALK than for DIATER and BIOCEN with Dp and Df. Conclusion: Dust mite extracts produced and standardized by DIATER, ALK-Abello and BIOCEN are similar with respect to allergenic potence.


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