Miranda MIC, Larralde CL, Niderhauser GA, Barboza QO, Ancer RJ

Language: Spanish
References: 17
Page: 188-195
PDF size: 337.98 Kb.

ABSTRACT

Background: Meningiomas are frequent neoplasias of the central nervous system and represent 13%-26% of intracranial tumors. They have been classified according to their histology and malignancy, since it is thought that they have different biological behavior.
Objective: To classify meningiomas according to the scheme proposed by the WHO 2007 and analyzed by age group, gender, and location.
Material and method: We studied 167 meningiomas from 162 patients seen at the Dr. Jose E. Gonzalez, University Hospital from January 1990 to December 2009.
Results: Meningiomas represent 20.1% of all tumors of the central nervous system seen in our hospital. According to histological grade 144 (88.8%) were grade I; 13 (8%) grade II; and 5 (3%) were grade III. Of the grade I meningiomas, transitional meningiomas were the most frequent histological type, followed by meningothelial meningiomas (24.6%). According to location, 143 (88.2%) were intracranial and 18 (11.1%) intraspinal. With regard to gender 107 (66%) cases were in women and 55 (33.9%) in men. Most were between 30 and 70 years of age.
Conclusions: A meningioma is a tumor with a large spectrum of morphological varieties. As in other series, meningiomas in our hospital represent the most frequent benign neoplasia of the central nervous system with more than 50% corresponding to grade I, and finding very little variations in comparison with previous publications. However, we believe it is important to report our findings to carry out a comparative analysis with other epidemiological studies.

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