2005, Number 3
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Rev Mex Patol Clin Med Lab 2005; 52 (3)
Toxoplasmosis: Reemergent parasite of the new millenium
Carrada BT
Language: Spanish
References: 39
Page: 151-162
PDF size: 237.54 Kb.
ABSTRACT
Although
Toxoplasma gondii infects a large proportion of the world’s animal and human populations, it is an uncommon cause of disease. Immunologically impaired individuals and congenitally infected fetus are at high risk for severe or life threatening toxoplasmosis.
T. gondii is a coccidian protozoan of felids with human and warm-blooded animals as intermediate hosts. It belongs to Apococomplexa, class Sporozoa and exist in nature in three forms: the oocyst, the tissue resistant cyst and the tachyzoite. The diagnosis of
T. gondii infection may be established by clinical-epidemiological study complemented by serologic tests, amplifications of specific nucleic acid sequences such as polymerase chain reaction, histologic demonstration of the parasite or by isolation of the organism. This illustrated paper presents the natural history and life cycle of
T. gondii, the Epidemiology-Ecology, the clinical categories and differential diagnosis with a short review of laboratory methods, prevention and treatment.
REFERENCES
Frenkel JK. Toxoplasmosis. En: Goldsmith R, Heyneman D (ed). Parasitología y medicina tropical. México, DF: Manual Moderno, 1995; 430-443.
Remington JS, McLeod R, Thullier P, Desmond G. Toxoplasmosis. In: Remington JS, Klein J (eds). Infectious disease of fetus and newborn infant. 5th ed. Philadelphia: WB Saunders, 2001; 205-346.
Atias A (ed). Parasitología médica. Cap 29: Toxoplasmosis. Santiago, Chile: Mediterráneo, 1998; 265-279.
Beaman MH, McCabe R, Wong SY, Remington JS. Toxoplasma gondii. En: Mandell GL, Bennett JE, Dolin R (eds). Enfermedades infecciosas y parasitarias. 4a ed. Bogotá, Colombia: Ed Panamer, 1997; 2754-2775.
McLeod R, Mack D, Brown C. Toxoplasma gondii. New advances in cellular and molecular biology. Exp Parasitol 1991; 72: 109-125.
Beaver ChP, Jung RC (eds). Clinical parasitology. 9th ed. Filadelfia: Lea & Febiger, 1984; 162-167.
Scholtyseck E (ed). Fine structure of parasitic protozoa. An atlas of micrographs, drawings and diagrams. Berlin: Springer-Verlag, 1979; 112-121.
Martínez-Barbosa I, Ruiz-González LA, Gutiérrez-Quiroz M, Fernández-Presas AM, Vázquez-Tsuji O. Frecuencia de ooquistes de Toxoplasma gondii en gatos domésticos de la Ciudad de México, DF y Área Metropolitana. Rev Mex Patol Clin 1996; 43: 121-127.
McLeod R, Mack D, Brown C. Toxoplasma gondii new advances in cellular and molecular biology. Exp Parasitol 1991; 72: 109-123.
Pizzi HL, Rico CM, Pessat OAM. Hallazgo del ciclo ontógenico selvático del Toxoplasma gondii en félidos salvajes (Oncifelis geofroyi, Felis colocolo y Felis eira) de la Provincia de Córdoba. Rev Milit Vet (B Aires) 1978; 25: 293-300.
Clumeck N. Some aspects of the epidemiolgy of toxoplasmosis and pneumocystosis in AIDS in Europe. Eur J Clin Microbiol Infect Dis 1991; 10: 177-178.
Velasco-Castrejon O, Salvatierra-Izaba B, Valdespino JL, Sedano-Lara AM, Galindo-Virgen S, Magos C et al. Epidemiología de la Toxoplasmosis en México. Sal Pub Mex 1992; 34: 222-229.
Kumate J. Toxoplasmosis. En: Kumate J, Gutiérrez G, Muñoz O, Santos-Preciado JI (eds). Manual de infectología clínica. 16a ed. México, DF: Méndez-Oteo, 2001; 683-694.
Dubey JP. A review: Toxoplasma in pigs. Vet Parasitol 1986; 19: 181-352.
Frenkel JK. Toxoplasmosis. In: Bindford CH, Connor DH. Pathology of tropical and extraordinary disease. Vol I. Washington, DC: Armed Forces Institute of Pathology, 1976; 284-300.
Hunter CA, Remington JS. Immunopathogenesis of toxoplasmic encephalitis. J Infect Dis 1994; 170: 1057-1067.
Porter SB, Sande M. Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. N Engl J Med 1992;327: 1643-1648.
Luft BJ, Hafner, R, Korzun AH, Leport C, Antoniskis D, Bosler EM et al. Toxoplasmic encephalitis with the acquired immunodeficiency syndrome. N Engl J Med 1993; 329: 995-1000.
Gongora-Rivera F, Santos-Zambrano J, Moreno-Andrade T, Calzada-López P, Soto-Hernández JL. The clinical spectrum of neurological manifestations of AIDS patients in Mexico. Arch Med Res 2000; 31: 393-398.
Soto-Hernández JL. Infecciones del sistema nervioso central. Gac Med Mex 2002; 138: 543-546.
Remington JS. Toxoplasmosis in the adult. Bull NY Acad Med 1974; 50: 211-227.
McCabe RE, Brooks RG, Dorfman RF, Remington JS. Clinical spectrum in 107 cases of toxoplasmic lymphadenopathy. Rev Infect Dis 1987; 9: 754-774.
Dorfman RF, Remington JS. Value of lymph-node biopsy in the diagnosis of acute acquired toxoplasmosis. N Engl J Med 1973; 289: 878-881.
24.Weiss L, Chen Y, Berry G. Infrequent detection of Toxoplasma gondii genome in toxoplasmic lymphadenitis: A polymerase chain reaction study. Hum Pathol 1992; 23: 154-158.
Remington JS, Narnett CG, Mikel M, Lunde MN. Toxoplasmosis and infectious mononucleosis. Arch Intern Med 1962; 110: 744-753.
Liesenfeld O, Wong SY, Remington JS. Toxoplasmosis in the Setting of AIDS. In: Barlett JG, Merigan TC, Bolognesi D (eds). Textbook of AIDS medicine. 2nd ed. Baltimore: Williams & Wilkins, 1999; 225-259.
Strittmatter C, Lang W, Wiestler OD, Klleihues P. The changing pattern of human immunodeficiency virus associated cerebral toxoplasmosis: A study of 46 post mortem cases. Acta Neurophatol 1992; 83: 475-481.
Herskovitz S, Siegel SE, Schneider AT. Spinal cord toxoplasmosis in AIDS. Neurology 1989; 39: 1552-1553.
Levy RM, Rosenbloom S, Perrett LV. Neuroradiologic findings in AIDS: A review of 200 cases. AJNR Am J Neuroradiol 1986; 147: 977-983.
Ciricillo SF, Rosenblum ML. Use of CT and MR imaging to distinguish intracranial lesions and to define the need for biopsy in AIDS patients. J Neurosurg 1990; 73: 720-724.
Martín-Sánchez AM. Otros protozoos de interés médico: Toxoplasma, Acanthamoeba, Naegleria y Pneumocystis. En: García-Rodríguez JA, Picaso JJ (eds). Microbiología médica. Tomo I. Madrid: Mosby, 1996; 767-776.
Ortega-Larrocea G, Arellanes-García L, Morales-Cantón V, Navarrete-Cámara M. Determinación de anticuerpos vs Toxoplasma gondii en vítreo y humor acuoso. Rev Mex Oftalmol 1994; 68: 186-190.
Montoya JG, Remington JS. Toxoplasmic chorioretinitis in the setting of acute acquired toxoplasmosis. Clin Infect Dis 1996; 23: 277-282.
Silveira C, Belfort R Jr, Burnier M Jr, Nussenblatt R. Acquired toxoplasmic infection as the cause of toxoplasmic retinochoroiditis in families. Am J Ophtalmol 1988; 106: 362-364.
Glasner PD, Silveira C, Kruszon-Moran D. An unusually high prevalence of ocular toxoplasmosis in Southern Brazil. Am J Opthal 1992; 114: 136-144.
Desmonts G, Couvreur J. Congenital toxoplasmosis: A prospective study of 378 pregnancies. N Engl J Med 1974; 290: 1110-1113.
Desmonts G, Couvreur J. Congenital toxoplasmosis. A prospective study of the offspring of 42 women who acquired toxoplasmosis during pregnancy. Pathophysiol Congenital Dis 1979; 1: 51-60.
Desmonts G. Acquired toxoplasmosis in pregnant women. Evaluation of the frequency of transmission of toxoplasma and of congenital toxoplasmosis. Lyon Med 1982; 248: 115-123.
Montoya JG. Laboratory Diagnosis of Toxoplasma gondii Infections and Toxoplasmosis. J Infect Dis 2002; 185 (suppl 1): S73-82.