2011, Number 5
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Rev Fac Med UNAM 2011; 54 (5)
Hypophyseal abscess: A case
González-Ibarra FP, Guzmán-Astorga CP, Leyva- Álvarez EA, Hernández-Félix CP, Estevan-Ortíz PD, Llanos-Navidad MG
Language: Spanish
References: 15
Page: 34-38
PDF size: 156.49 Kb.
ABSTRACT
Pituitary abscesses are defined as the affection of the pituitary gland by an intrasellar suppurative process caused by an infectious agent. Pituitary abscesses represent less than 1% of the pathologies of the sellar region, the clinical manifestations are due to pituitary dysfunction or mass effect. The diagnosis in most of the cases is only after transsphenoidal drainage which is the therapeutic approach of choice, being underdiagnosed and becoming a disease with high mortality if the right and appropriate treatment is not instituted. Case report. A case of a 38-year-old-female patient with amenorrhea of one year of evolution, galactorrhea, headache and visual field deficits manifested by bitemporal hemianopsia is reported. Magnetic resonance imaging showed an image compatible with pituitary adenoma, a transsphenoidal approach was performed and histopathologic report confirmed a brain abscess. Antibiotic therapy was empirically started with vancomycin, metronidazole and ceftriaxone at meningeal doses, failed to get the agent in cultures. Conclusions. Pituitary abscesses are a potentially curable disease that present as a sellar mass, most receive the appropriate therapy by transsphenoidal approach and in most of the cases this procedure gives the definitive diagnosis and treatment simultaneously.
REFERENCES
Hanel R, Koerbel A, Prevedello D, Moro MS, Araujo JC. Primary pituitary abscess: case report. Arq neuro-psiquiatr. 2002;60:861-5.
Vates GE, Berger M, Wilson C. Diagnosis and management of pituitary abscess: a review of twenty-four cases. J Neurosurg. 2001;95:233-41.
Domingue JN, Wilson CB. Pituitary abscesses. Report of seven cases and review of the literature. J Neurosurg. 1977;46:601-8.
Jadhav RN, Dahiwadkar HV, alande DA. Abscess formation in invasive pituitary adenoma: case report. Neurosurgery. 1998;43:616-9.
Heary RF, Maniker AH, Wolansky LJ. Candidal pituitary abscess: case report. Neurosurgery. 1995;36:1009-12.
Thomas N, Wittert GA, Scott G, Reilly PL. Infection of a Rathke’s cleft cyst: a rare cause of pituitary abscess. Case illustration. J Neurosurg. 1998; 89:682.
Jain KC, Varma A, ahapatra AK. Pituitary abscess: a series of six cases. Br J Neurosurg. 1997;11:139-43.
Arseni C, Dănăilă L, Carp N, hitescu Ghitescu M, Istrati C. Intrasellar abscess. Neurochirurgia. 1975;18:207-13.
Becker GL Jr, Knep S, Lance KP, Kaufman L. Amebic abscess of the brain. Neurosurgery. 1980;6:192-4.
Fong TC, Johns RD, Long M, et al. CT of pituitary abscess. Am J Roentgenol. 1985;144:1141-2.
Enzmann DR, Sieling RJ. CT of pituitary abscess. A JNR Am J Neuroradiol. 983;4:79-80.
Bassard D, Himed A, Badet C, et al. MRI and CT in a case of pituitary abscess. J Neurosurg. 1992;46:601-8.
Abs R, Parizel PM, Verlooy J, et al. Magnetic resonance characterization of a long-standing pituitary abscess. J Endocrinol Invest. 1993;16:635-7.
Boggan J, Wilson C. Pituitary abscess. Wilkins RH & Renganchary ss editors. Neurosurgery. New york: mcgraw-hill; 1985. cap. 247, p. 1967-8.
Gatell JM, Esmatjes E, Serra C, Aymerich M, San Miguel JG. Diabetes insipidus and anterior pituitary dysfunction after staphylococcal meningitis and multiple brain abscesses. J Infect Dis. 1982;146(1):102.