2011, Number 2
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Rev Endocrinol Nutr 2011; 19 (2)
Tumor size is not associated with postoperative pituitary hormonal deficiencies in children with craniopharyngiomas
Bahena-García AL, Tamez-Pérez HE, Sánchez-Sánchez LM, Quintanilla-Flores DL, Hernández-Coria MI, Cisneros-Franco JM, Palacios-Saucedo G, Escudero-Rendón AJ
Language: Spanish
References: 20
Page: 58-61
PDF size: 89.03 Kb.
ABSTRACT
Background: Craniopharyngioma is the third most common intracranial tumor in childhood and the most common pediatric tumor in the sellar region. After surgery, most patients develop hormonal deficiencies that require treatment.
Objective: To evaluate whether tumor size over 4 cm is associated with the development of postoperative pituitary hormonal deficiencies in children with craniopharyngioma.
Research design and methods: We included pediatric patients with the diagnosis of craniopharyngioma who underwent surgery between March 2007 and March 2009. We analyzed variables such as age, gender, type of surgery, neurologic deficit before surgery and postoperative pituitary hormonal deficiencies. The patients were divided according to tumor size in group 1 (≤ 4 cm) and group 2 (› 4 cm).
Results: Twenty-two patients were included, 13 in group 1 and 9 in group 2. We did not find statistical differences between tumor size and age, gender, type of surgery and neurologic deficit. When analyzing each hormonal deficiency we did not find statistical differences between these and the variables studied.
Conclusions: No associations were found between tumor size and postoperative pituitary hormonal deficiencies in children with craniopharyngioma.
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