2011, Number 3
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Rev Mex Anest 2011; 34 (3)
What kind of adjuvant for sedation: dexmedetomidine for abdomen and lower limb surgery?
Oriol-López SA, Hernández-Bernal CE
Language: Spanish
References: 26
Page: 189-195
PDF size: 107.86 Kb.
ABSTRACT
Using locoregional anesthesia, due to the surgery duration and the patient type, it’s common the administration of sedation, this aims to produce comfort to the patient and reducing risks such as: respiratory depression, produce amnesia and induce sleep, reducing anxiety and stress during the surgical act. The risks are related to the drugs used, by the following mechanisms: dose dependent and synergy between different drugs, which are used in higher percentage: combinations of opioids, benzodiazepines and hypnotic as propofol, also the dexmedetomidine, an a2 adrenergic receptor, powerful and highly selective agonist drug, with analgesic and sedative properties but no respiratory effects.
Methodology: 82 patients randomized trial included in 2 groups, they were managed with dexmedetomidine or fentanyl and lidocaine, epidural via, measuring degree of sedation with Wilson scale, Bromage, heart rate, medium blood pressure and oxygen saturation.
Results: The obtained degree of sedation was higher in the group of dexmedetomidine p ‹ 0.05, obtained similar levels of Bromage, with mayor hemodynamic stability than patients with fentanyl.
Conclusion: The epidural dexmedetomidine provides a degree of useful sedation in patients undergoing loco regional anesthesia, without risk of respiratory depression.
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