Lara GEA, Chapa IM, Criales VSA, Moguel MNI, González AAJ, Vázquez LJ

Language: Spanish
References: 11
Page: 233-238
PDF size: 304.41 Kb.

ABSTRACT

Objective: Determining the benefit of the hepatic border nodularity finding for the prediction of cirrhosis in patients with hepatitis C virus (HCV).
Material and methods: 42 cases of patients with HCV submitted to biopsy for diagnosis of cirrhosis were retrospectively examined. Prevalence of the hepatic border nodularity finding was established, as well as its histopathological correlation with the METAVIR1 classification. Sensitivity and specificity of the finding and its predictive positive and negative value were determined.
Results: Of the 42 studies, 6 had fibrosis (cirrhosis), 15 were normal and 21 changes of the portal entryway, with no fibrosis. Sensitivity and specificity of the finding was 16 and 92% respectively and its predictive positive and negative value was 25 and 85%.
Conclusion: The ultrasonographic hepatic border nodularity pattern is very accurate to identify cirrhosis in patients with HCV, although its benefit to predict early changes or to exclude them is still limited.

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