Morán S, Rodríguez-Leal G, Ramos MH, Duque MX, Guevara L, Uribe M

Language: Spanish
References: 33
Page: 6-9
PDF size: 129.91 Kb.

ABSTRACT

Epidemiological studies in different socioeconomic groups and regions of Mexico have shown that significant differences in serum cholesterol values exist between them. In those regions with higher cholesterol values a there is a greater prevalence of diseases associated with atheroesclerosis. Considering this heterogeneous background, we performed a prospective study that included 2,111 apparently healthy individuals, to determine the prevalence of hypercholesterolemia (HC) and clinical associations. Two groups were formed according to cholesterol values › 240 mg/dL and under ‹ 200 mg/dL. All participants in the study answered a questionnaire that included demographic data, alcohol consumption, smoking habit, contraceptive use and presence of hypertension and/or diabetes mellitus. Serum lipid profile and liver ultrasound were performed in all individuals. Multiple logistic regression analysis was performed to explore associations, prevalence of HC in this population was 23.6%. Mean serum cholesterol in women was 204 ± 48 mg/dL (X ± DE) and 214 ± 45 mg/dL in men. A positive association was found between HC and male sex, Odds Ratio (OR) = 1.90, age (OR = 1.047), obesity (OR = 1.78) Ad hypertrigliceridemia (OR = 10.25). This prevalence in inferior to that reported from Finland or USA.

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