Rodríguez-Leal GA

Language: Spanish
References: 47
Page: 84-89
PDF size: 55.65 Kb.

ABSTRACT

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the intestine of unknown etiology in which patients suffer from intestinal and extraintestinal signs and symptoms. It is becoming increasingly apparent that chronic gut inflammation may result from a dysregulated immune response toward components of the normal intestinal flora, resulting in a sustained overproduction of proinflammatory cytokines and mediators. This review discusses the basic immune mechanisms involved in the regulation of inflammatory responses in the gut and describes epidemiological data associated with this kind of diseases.

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