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Organo Oficial de la Sociedad Mexicana de Urología

2011, Number 2

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Rev Mex Urol 2011; 71 (2)

Nasal-type NK non-Hodgkin lymphoma in the testis

Busto-Martín L, Pombo-Otero J, Busto-Castañón L

Language: Spanish
References: 14
Page: 106-110
PDF size: 285.64 Kb.


ABSTRACT

Objective: To present a case of nasal-type NK-cell tumor arising in the testis along with a review of the published biomedical literature.
Methods and result: Patient is a sixty-eight-year-old man with no prior urological history who sought medical attention at the authors’ department for inflammation of the right testis of 11-month progression affecting scrotal skin that responded poorly to antibiotic treatment. Inguinal orchiectomy was carried out and affected skin was resected. Definitive histological diagnosis was large cell nasal-type, NK cell non-Hodgkin lymphoma. The Hematology Department later carried out extension study that confirmed lymphoma diagnosis through blood smear. Patient was staged and then received three cycles of cyclophosphamide, doxorubicin, oncovin, and prednisone chemotherapy and intrathecal prophylaxis. At follow-up twenty months from the time of symptom onset patient has not presented with disease involvement in lymph nodes or in any other organ.
Conclusions: Nasal T/NK-cell lymphomas are rare tumors in the Mexican population and extranasal presentation is extremely rare with only twelve cases of testicular presentation reported in the literature reviewed. Anatomicopathological study by means of immunohistochemistry is essential for classifying these lymphomas given that this type is characterized by rapid dissemination and poor treatment response.


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