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2011, Number 2

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Enf Infec Microbiol 2011; 31 (2)

Entamoeba histolytica and it´s cell/parasite relationship

Campos PJM, Sánchez MV, Villalba MJDA

Language: Spanish
References: 84
Page: 63-70
PDF size: 231.12 Kb.


ABSTRACT

In this review, we describe some current data from the series of events that occur in the host parasite relationship that is set to amebiasis, infection endemic in our country, described in medical literature since the days of Hippocrates, which is one of the three most common causes of death from parasitic diseases. This disease has different clinical pictures, but even today much is unknown about host parasite relationship leading to the production of lesions. In host-parasite interaction of mucin release from intestinal mucosa, the presence of the resident bacterial flora in the intestine, the complement system and immune response represent some of the barriers of defense against E. histolytica, although several reports have documented the modulation of this response by the amoeba primarily through its cysteine proteases and lectins. Therefore, probably the pathogenesis of the disease is due to the combined effects of the conditions presented by the host to control infection, as well as to the chara cteristics of the parasite itself.


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