Gómez GMÁ, Tarín ALC, Cantú RO, Gutiérrez ACH, Méndez RN, Gómez AD

Language: Spanish
References: 11
Page: 212-215
PDF size: 255.83 Kb.

ABSTRACT

Absolute lymphocytosis raises the possibility of hematological malignancy and generally warrants further investigation. In this study to better correlate clinical variables with the frequency of neoplastic lymphoid process, we retrospectively reviewed flow cytometry analysis from peripheral blood specimens on 52 patients that had been deemed suspicious for a lymphoproliferative process after peripheral smear review. Of 52 total cases, 28 were male, the median age was 67 years and the range was 31-90 years. We found that 41 patients had chronic lymphocytic leukemia, 6 mantle cell lymphoma and only one case of hairy cell leukemia, marginal zone B cell lymphoma, splenic marginal zone B cell lymphoma, follicular lymphoma and diffuse large B cell lymphoma. Advances in flow cytometry analysis have dramatically improved the ability to detect aberrant lymphocyte populations in peripheral blood samples and help to a better selection of the treatment options.

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