2011, Number 1
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An Med Asoc Med Hosp ABC 2011; 56 (1)
Giant chorioangioma of the placenta associated with Pierre Robin sequence
Smeke BJ, Linder EC, Meneses RA, Valdespín FC, González CJ, Chaya HM, Ibarrola BAE
Language: Spanish
References: 23
Page: 38-43
PDF size: 291.54 Kb.
ABSTRACT
Chorioangioma is the most common benign tumor of non-trophoblastic origin of the placenta. It rarely surpasses 5 to 6 centimeters in length and, when it happens, is referred to as giant chorioangioma. This type of tumor confers more complications for the patient when compared with normal chorioangioma, including preterm labor, polyhidramnios, and intrauterus growth restriction. Different types of congenital abnormalities have been associated to the chorioangioma, however, there has never been a case reporting its relationship to the Pierre Robin sequence. This sequence is a congenital malformation designated by a combination of birth defects characterized by micrognatia, glossoptosis, and cleft lip. The association between these two anomalies could be the consequence of a mechanical compression effect over the normal embryological development. The fact is that the physiopathology of Pierre Robin sequence and giant chorioangioma are still under continuous research in order to know their origin and consequences and facilitate the determination of a possible association.
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