2011, Number 1
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Enf Infec Microbiol 2011; 31 (1)
Human papilomavirus genotypes in Mexican women from south of Mexico
Domínguez AS, Sánchez GRA, Becerra VG, Flores ALC, Lugo TA, Canseco ÁLM, Trujillo MKC, Serrano GE, Espinoza RM
Language: Spanish
References: 29
Page: 6-10
PDF size: 368.58 Kb.
ABSTRACT
Background. The genotypes of Human Papillomavirus (HPV) 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 66 have been implicated in the development of cervical cancer (CC). Mexico and Central America have one of the highest incidences of cervical cancer in the world, and Chiapas has the highest mortality rate in Mexico. The aim of this study was to determine the frequency of HPV genotypes in women living at the border state of Chiapas with the Republic of Guatemala.
Material and methods. We performed a prospective, descriptive and cross sectional study in female population who attended the Pap study, in the municipality of Frontera Comalapa, Chiapas. Socio-economic variables were obtained. HPV DNA was identified by PCR. HPV-positive samples were genotyped, using a commercial kit that simultaneously amplifies up to 8 viral genotypes.
Results and conclusions. 225 samples were examined, 5/225 (2.22%) were positive for HPV, 3 of these were genotyped identifying genotypes 11, 18, and 33. 66% of the study population had not completed basic education. We obtained the frequency of HPV genotypes and analyzed socio-demographic variables of the study population.
REFERENCES
De Villiers E, Fauquet C, Broker T, Bernard H, Zur Hausen H. “Classification of papillomaviruses”. Virology 2004; 324: 17-27.
Bernard H. “The clinical importance of the nomenclature, evolution and taxonomy of human papillomaviruses”.J Clin Virol 2005; 32: S1-S6.
Bosch FX, Manos MM, Muñoz N, Sherman M, Jansen AM, et al. “International Biological Study of Cervical Cancer (IBSCC) Study group. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective”. J Natl Cancer Inst 1995; 87: 796-802.
Lazcano Ponce E, Herrero R, Muñoz N, Cruz A, Keerti VS, et al. “Epidemiology of hpv infection among mexican women with normal cervical cytology”. Int J Cancer 2001; 91, 412-420.
Velázquez Márquez N, Paredes Tello MA, Pérez Terrón H, Santos López G, Reyes-Leyva J, et al. “Prevalence of human papillomavirus genotypes in women from a rural region of Puebla, Mexico”. Int J Infect Dis 2009; 13(6): 690-695.
Hernández Girón C, Smith JS, Lorincz A, Arreola Cháidez E, Lazcano E, et al. “The prevalence of high-risk HPV infection in pregnant women from Morelos, Mexico”. Salud Pública Mex 2005; 47: 423-429.
Canal Canche J, Rosado López I, Suárez NG, Colli Acosta G, Conde-Ferráez L, et al. “High prevalence and low E6 genetic variability of human papillomavirus 58 in women with cervical cancer and precursor lesions in Southeast Mexico”. Mem Inst Oswaldo Cruz 2010; 105(2): 144-148.
Walboomers JMM, Jacobs MV, Manos M, Bosch FX, Kummer JA, et al. “Human papillomavirus is a necessary cause of invasive cervical cancer worldwide”. J Pathol 1999; 189: 12-19.
Parkin M, Pisani P, Ferlay J. “Estimates of the worldwide incidence of 25 major cancers in 1990”. Int J Cancer 1999; 80: 827-841.
Palacio-Mejía LS, Lazcano-Ponce E, Allen-Leigh B, Hernández-Ávila M. “Regional differences in breast and cervical cancer mortality in Mexico between 1979- 2006”. Salud Publica Mex 2009; 51 suppl 2: S208-S219.
Schiffman M, Castle PE, Jerónimo J, Rodríguez A, Wacholder S. “Human papillomavirus and cervical cancer”.The Lancet 2007; 370: 890-907.
Sterling JC. “Human papillomaviruses and skin cancer”. J Clin Virol. 2005; Mar; 32 Suppl 1:S67-S71.
Ferreccio C, Corvalán A, Margozzini P, Viviani P, González C, et al. “Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples”. BMC Public Health 2008; 8: 78.
Sijvarger CC, González JV, Prieto A, Messmer AG, Mallimaci MC, et al. “Epidemiología de la infección cervical por virus papiloma humano en Ushuaia, Argentina”. Rev Argent Microbiol 2006; 38: 19-24.
Tábora N, Bakkers JMJE, Quint WGV, Massuger LFAG, Matute JA, et al. “Human papillomavirus infection in Honduran women with normal cytology”. Cancer Causes Control 2009; 20:1663-1670.
López Revilla R, Martínez Contreras LA, Sánchez Garza M. “Prevalence of high-risk human papillomavirus types in Mexican women with cervical intraepithelial neoplasia and invasive carcinoma”. Infectious Agents and Cancer 2008; 3: 3.
Flores YN, Bishai DM, Shah KV, Lazcano-Ponce E, Lörincz A, et al. “Risk factors for cervical cancer among HPV positive women in Mexico”. Salud Pública Mex 2008; 50(1): 49-58.
Organización Panamericana de la Salud. Estrategia de Cooperación con México de la OPS/OMS para el periodo 2005-2009. México, DF: OPS/ OMS. 2005; 45-50.
Grupo Guatemala-México Migración y desarrollo. Los flujos migratorios. 2010.[http://mexicoguatemala.colmex. mx/index.php?option=com_content&view=articl e&id=60&Itemid=62]
The American College of Obstetricians and Gynecologists: ACOG Education PamphletAP161. [http://www. acog.org/publications/patient_education/bp161.cfm].
Van Doorn LJ, Molijn A, Kleter B, Quint W, Colau B. “Highly Effective Detection of Human Papillomavirus 16 and 18 DNA by a Testing Algorithm Combining Broad-Spectrum and Type-Specific PCR”. J Clin Microbiol 2006; 44(9): 3292-3298.
Fontaine V, Mascaux C, Weyn C, Bernis A, Celio N, et al. “Evaluation of Combined General Primer-Mediated PCR Sequencing and Type-Specific PCR Strategies for Determination of Human Papillomavirus Genotypes in Cervical Cell Specimens”. J Clin Microbiol 2007; 45(3): 928-934.
De Roda-Husman AM, Walboomers JMM, van den Brule AJC, Meijer CJLM, Snijders PJF. “The use of general primers GP5 and GP6 elongated at their 3’ ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR”. J Gen Virol 1995;76: 1057-1062.
Fuessel AL, He Q, Rady PL, et al. “Nested PCR with the PGMY09/11 and GP5 (+)/6(+) primer sets improves detection of HPV DNA in cervical samples”. J Virol Methods 2004; 122(1): 87-89.
Tirado Gómez LL, Mohar Betancourt A, López Cervantes M, García Carrancá A, Franco-Marina F, et al. “Factores de riesgo de cáncer cervicouterino invasor en mujeres mexicanas”. Salud Pública Mex 2005; 47: 342-350.
Atalah E, Urteaga C, Rebolledo A, Villegas RA, Medina E, et al. “Diet, smoking and reproductive history as risk factor for cervical cancer”. Rev Med Chil 2001; 129: 597-603.
Faggiano F, Partanen T, Kogevinas M, Boffetta P. “Socioeconomic differences in cancer incidence and mortality”. IARC Sci Publ 1997; 138: 65-176.
Palacio-Mejía LS, Rangel-Gómez G, Hernández-Avila M, Lazcano-Ponce E. “Cervical cancer, a disease of poverty: Mortality differences between urban and rural areas in Mexico”. Salud Publica Mex 2003; 45 suppl 3:S315-S325.
Cruz-Piñeiro R. “Mexican border cities and migration flows”. The James A. Baker III, Institute for public policy 2009: 3-29.