Manzanilla-García HA, Maldonado-Ávila M, Aguilar-Barradas J, Lira-Dale A

Language: Spanish
References: 49
Page: 307-313
PDF size: 316.08 Kb.

ABSTRACT

Bladder cancer is the second most common cancer in the urinary tract and the most frequent histological type is transitional cell carcinoma (TCC). Approximately 70% of these cancers are superficial (no evidence of muscle invasion) in situ (Tis), Ta and T1 carcinomas. The biological behavior of these tumors varies from slight recurrence tendency to a high degree of recurrence and progression. Although transurethral resection of the bladder tumor (TURBT) is the standard treatment, a large number of complementary treatments based on the administration of different intravesical chemotherapeutic and immunotherapeutic agents, including Bacillus Calmette-Guérin (BCG) have been established. The most appropriate management consensus has yet to be determined. The present article reviews the use of BCG in superficial bladder cancer in relation to its indications, contraindications, action mechanism and different results in distinct stages of the disease.

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