medigraphic.com
Organo Oficial de la Sociedad Mexicana de Urología

2009, Number 3

<< Back Next >>

Rev Mex Urol 2009; 69 (3)

Cancer of the female urethra

García-Morúa A, Gutiérrez-García JD, Valdés-Sepúlveda F, Jaime-Dávila R, Gómez-Guerra LS.

Language: Spanish
References: 19
Page: 127-130
PDF size: 1961.56 Kb.


ABSTRACT

Introduction: Primary cancer of tethra is rare and represents about 0.02% of all neoplasia found in women and the majority of them are squamous cell carcinomas. Diagnosis is difficult due to the fact that the disease has usually reached advanced stage. Prognosis is dependent on clinical stage at the moment of diagnosis and tends to be poor.
Clinical case: This case is a 56-year-old female patient diagnosed with poorly defined primary papillary transitional cell carcinoma of the urethra with positive lymph nodes.
Discussion: Primary carcinoma of the urethra is a rare tumor with a higher incidence in women than in men (4:1). It most commonly appears in the sixth decade of the patient’s life. Chronic inflammatory processes and human papillomaviruses 16 and 18 have been associated as possible etiological factors. By 2004 one thousand two hundred cases had been described in women and 600 cases in men. Disease stage is the most important survival prognosis factor. Treatment is determined by the sex of the patient, disease stage, histological type, extension and localization.


REFERENCES

  1. Swartz MA, Porter MP, Lin DW, Weiss NS. Incidence of primary urethral carcinoma in the United States. Urology 2006;68:1164-68.

  2. Gómez- Díaz ME,Castaño-González-Costo D, Cuervo-Calvo J, Muruamendiaraz V. Cáncer de uretra femenino. Aportación de un caso y revisión de la literatura Arch Esp Urol 2002;55(5):568-71.

  3. Maier U, Dorfinger K, Susani M. Clear cell adenocarcinoma of the female urethra J Urol 1998;160:492-3.

  4. Thyavihally YB, Wuntkal R, Bakshi G, Uppin S, Tongaonkar HB. Primary carcinoma of the female urethra: single center experience of 18 cases Jpn J Clin Oncol 2005;35(2):84-7.

  5. Tazi K, Karmouni T, Koutani A, Ibn Attya A, et al. Cancer of the female urethra. Report of 2 new cases. Prog Urol 2000;10(6):1217-9.

  6. Segura-Huerta A, Molina-Saera J, Abad P, Ariño P, et al. Carcinoma Uretral con extensión locorregional importante. ¿Cómo manejamos una patología infrecuente? Actas Urol Esp 2004;28(1):57-61.

  7. Weghaupt K, Gestner GJ, Kucera H. Radiation therapy for primary carcinoma of the female urethra: A survey over 25 years. Gynecol Oncol 1984;17:58-63.

  8. Wiener JS, Walther PJ. The association of oncogenic human papilomavirus with urologic malignancy. The controversies and clinical implications. Surg Oncol Clin North Am 1995;4:257-76.

  9. Mostofi FK, Davis CR Jr, Sesterhenn IA. Carcinoma of the male and female urethra. Urol Clin North Am 1992;19:347-58.

  10. Carroll PR, Dixon CM. Surgical anatomy of the male and female urethra. Urol Clin North Am 1992;19:339-46.

  11. Narayan P, Konety B. Surgical treatment of female urethral carcinoma. Urol Clin North Am 1992;19:373-82.

  12. Kuettel MR, Parada DS, Harter KW, Rodgers JE, et al. Treatment of female urethral carcinoma in medically inoperable patients using external beam irradiation and high dose rate intracavitary brachytherapy. J Urol 1997;157:1669-71.

  13. Eisenberger MA. Chemotherapy for carcinoma of the penis and urethra.. Urol Clin North Am 1992;19:333-8.

  14. Lutz ST, Huang DT. Combined chemoradiotherapy for locally advanced squamous cell carcinoma of the membranous urethra: A case report. J Urol 1995;153:1616-8.

  15. Tran LN, Krieg RM, Szabo RJ. Combination chemotherapy and radiotherapy for a locally advanced squamous cell carcinoma of the urethra: A case report. J Urol 1995; 153:422-3.

  16. Dalbagni G, Donat SM, Eschwegw P, Herr HW, et al. Results of high dose rate brachytherapy, anterior pelvic exenteration and external beam radiotherapy for carcinoma of the female urethra. J Urol 2001;166:1759-61.

  17. Lee KC. Carcinoma of the female urethra responsive to moderate dose chemoradiotherapy. J Urol 2000;163:905-6.

  18. Milosevic MF, Warde PR, Banerjee D, Gospodarowicz MK, et al. Urethral carcinoma in women: Results of treatment with primary radiotherapy. Radiother Oncol 2000; 56(1):29-35.

  19. Feltes-Ochoa JA, Blanco-Carballo O, Tejido-Sánchez A, Conde-Gallego E, et al. Adenocarcinoma de uretra femenina: presentación de dos casos y revisión de la literatura. Arch Esp Urol 2005;58(7):677-82.




2020     |     www.medigraphic.com