2010, Number 6
Supervivencia del paciente e injerto renal al año de trasplante de donante fallecido; comparación con resultados de donante vivo
Ticona-Garrón AB, Álvarez-Rangel LE, Jiménez-Domínguez A, Cruz-Santiago J, Medina-Uicab C, Meza-Jiménez G, Martínez-Romo ME, Arancibia-Bolaños FJ
Language: Spanish
References: 13
Page: 347-353
PDF size: 1233.99 Kb.
ABSTRACT
Introduction: In deceased-donor kidney transplantation, patient and kidney graft survival at one, five, and ten years is inferior to that of live-donor transplantation. The objective of the present study was to determine patient and graft survival results in deceased-donor kidney transplantation and compare them with results from live-donor kidney transplantation at the authors’ medical center.Methods: A retrospective study was carried out on deceased-donor kidney transplantation recipients at the Hospital de Especialidades “Dr Antonio Fraga Mouret” of the Centro Médico Nacional La Raza. Live-donor kidney transplantation recipients from the same time period were used as the control group. Graft and patient survival were analyzed in recipients of deceased-donor kidney transplantation at twelve months using Kaplan-Meier actuarial survival curves. Results were compared with those obtained from live-donor transplantation recipients.
Results: The study included four hundred and fifty-two kidney transplantations (thirty-one from deceased donors and four hundred and twenty-one from live donors). Graft survival was 83.9% in the deceased-donor group and 94.3% in the live-donor group at twelve months after transplantation and patient survival was 90.3% in the deceased- donor group and 96.9% in the live-donor group.
Conclusions: Patient and kidney graft survival at twelve months after deceased-donor kidney transplantation was significantly lower than patient and graft survival in livedonor transplantation. These results are similar to those reported in other transplantation centers worldwide.
REFERENCES
2007 Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1994-2005. Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation, Rockville, MD; United Network for Organ Sharing, Richmond, VA; University Renal Research and Education Association, Ann Arbor, MI.