2009, Number 12
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Ginecol Obstet Mex 2009; 77 (12)
Phyllodes tumor: institutional experience
Aranda FC, Olaya GEJ, Colin VA, Miguel PPS
Language: Spanish
References: 26
Page: 567-572
PDF size: 358.03 Kb.
ABSTRACT
Background: Phyllodes tumor represents one of the fibroepithelial breast neoplasms that accounts for 0.3% to 1% of the breast tumors.
Objective: To describe a case series of patients with phyllodes tumor diagnosis.
Material and methods: We retrospectively reviewed the medical records of patients that had confirmed histological phyllodes tumor collected over a period of ten years.
Results: The incidence was 0.8%, 12.5% of cases corresponded to malignant phyllodes. The average age was 35 years (range 14-50 years); the most frequent site of localization was the superior and external quadrant of the breast; the average tumoral size by image studies (ultrasound or mastography) and by direct measurement was 61 mm (13-150mm) and 77 mm (30-300mm), respectively. One case coexisted with pregnancy.
Conclusions: It is a rare neoplasm, and the clinician must be aware of its timely diagnosis and treatment, if not some cases will develop breast deformity and some others will be borderline or malignant.
REFERENCES
Bernstein L, Deapen D, Ross RK. The descriptive epidemiology of malignant cytosarcoma phyllodes tumors of the breast. Cancer 1993;71:3020-4.
Reinfuss, M, Mitus J, Duda K. The treatment and prognosis of patients with phyllodes tumors of breast. Analysis of 170 cases. Cancer 1996;77:910-6.
Lerwill MF. Biphasic lesions of the breast. Sem Diag Pathol 2004;21:48-56.
De Roos W, Kye P, Dent D. Factors leading to local recurrence or death after surgical resection of phyllodes tumors of the breast. Br J Surg 1999;86:396-9.
Dillon M, Quinn C, McDermott E, O’Doherty A, O’Higgins N, Hill A. Needle core biopsy in the diagnosis of phyllodes neoplasm. Surgery 2006;140:779-84.
Chua C, Thomas A, Ng B. Cystosarcoma phyllodes; a review of surgical options. Surgery 1989;105:141-7.
Liberman L, Bonaccio E, Hmele-Bena D, Abramson A, Cohen M. Benign and malignant phyllodes tumors: mammographic and sonographic findings. Radiology 1996; 198:121-4.
Farria D, Gorczyca D, Barsky S, Sinha S, Basset L. Benign phyllodes tumor of the breast. MR imaging features. Am J Roentgenol 1996;167:187-9.
Chao TC, Lo YF, Chen SC, Chen MF. Sonographic features of phyllodes tumors of the breast. Ultrasound Obstet Gynecol 2002;20:64-71.
Chaney, A, Pollack A, McNeese. Primary treatment of cystosarcoma phyllodes of the breast. Cancer 2000;89:1502-11.
Paredes A, García K. Cistosarcoma phyllodes: Análisis de 9 casos clínicos y revisión bibliográfica. Cancerología 1989; 35:805-9.
Mangi A, Smith B, Gadd M, Tanabe K, Ott M, Souba W. Surgical management of phyllodes tumors. Arch Surg 1999; 134:487-93.
Serrano J. Miranda H, Sandoval F, De la Garza J. Tumor phyllodes comunicación de 110 casos. Revisión de la literatura. Rev Inst Nac Cancerol 1988;34:523-31.
Rowell M, Perry RR, Hsiu J, Barranco S. Phyllodes tumors. AM J Surg 1993;165:376-9.
Ben Hassouna J, Damak T, Gamoudi A, Chargui R, et al. Phyllodes tumors of the breast: a case series of 106 patients. Am J Surg 2006;192:141-7.
Norris HJ, Taylor HB. Relationship of histologic features to behavior of cystosarcoma phyllodes – analysis of 94 cases. Cancer 1967;20:2090.
Aranda C, Sotelo M, Torres A, Zarate M. Tumor phyllodes y embarazo: reporte de un caso. Ginecol Obstet Mex 2005; 73:387-92.
Pietruzka M, Barnes L. Cystosarcoma phyllodes – a clinicopathologic analysis of 42 cases. Cancer 1978;41:1974-83.
Fou A, Schnabel FR, Hamele-Bena D, Wei XJ, et al. Longterm outcomes of malignant phyllodes tumors patients: an institutional experience. Am J Surg 2006;192:492-5.
Rajan P, Cranor M, Rosen P. Cystosarcoma phyllodes in adolescent girls and young women. A study of 45 patients. Am J Surg Pathol 1998;22:64-9.
Hawkins RE, Schofield JB, Fisher C, et al. The clinical and histological criteria that metastasis from cystosarcoma phyllodes. Cancer 1992;69:141-7.
Umekita Y, Yoshida H. Immunohistochemical study of hormone receptor and hormone-regulated protein expression in phyllodes tumour: comparison with fibroadenoma. Virchows Arch 1998;433:311-4.
Tse G, Lee C, Kung F. Hormonal receptors expression in epithelial cell of mammary phyllodes tumours correlates with pathologic grade of the tumor; a multicenter study of 143 cases. Am J Clin Pathol 2002;118:552-6.
Tse G, Hoon Tan P. Recent advances in the pathology of fibroepithelial tumours of the breast. Curr Diag Pathol 2005; 11:426-34.
Tan PH, Jayabaskar R, Chuah KL, et al. Phyllodes tumors of the breast; the role of pathologic parameters. Am J Clin Pathol 2005;123:1-12.
Erogle E, Irkkan C, Ozsoy M, Eroglu F. Phyllodes tumor of the breast: case series of 40 patients. Eur J Gynaecol Oncol 2004; 25:123-5.