2010, Number 6
<< Back Next >>
salud publica mex 2010; 52 (6)
Frequency of respiratory viruses and clinical characteristics in children attending a care center in Mexico City
Wong-Chew RM, Farfán-Quiroz R, Sánchez-Huerta JL, Nava-Frías M, Casasola-Flores J, Santos-Preciado JI
Language: Spanish
References: 43
Page: 528-532
PDF size: 129.07 Kb.
ABSTRACT
Objective. To describe the frequency of respiratory viruses and clinical characteristics in children with respiratory signs and symptoms in a tertiary care center in Mexico.
Material and Methods. Patients with a clinical diagnosis of respiratory infection and a positive immunofluorescence result (Light Diagnostics) from January 2004 to October 2006 were included.
Results. From the 986 nashopharyngeal samples, 138 (14%) were positive by immunofluorescence. The frequency was: 80% RSV, 8% parainfluenza 1, 5% parainfluenza 3, 2% adenovirus, 2% influenza A, 1% parainfluenza 2 and 1% influenza B.
Conclusions. Respiratory viruses were detected in 14% of samples tested. RSV was the most frequently identified virus and was associated with pneumonia and bronchiolitis in children younger than 3 years old.
REFERENCES
Feigin R, Cherry J. Textbook of pediatric infectious diseases. 5a edición. Philadelphia: WB Saunders, 2005;vol. 1:137-270.
WHO, World Health Report 2005 [monografía en internet]. Geneva: World Health Organization, 2005 [consultado 2007 mayo 20]. Disponible en: http://www.who.int/whr/2005/en/index.html
Instituto Nacional de Estadística y Geografía. Anuarios de mortalidad y morbilidad del INEGI [monografía en internet] [consultado 2007 mayo 20]. Disponible en: http://www.inegi.org.mx/est/contenidos/espanol/soc/ sis/sisept/default.aspx?t=msal06&s =est&c=3357
Dirección General de Epidemiología. Anuarios de morbilidad [monografía en internet] [consultado 2007 agosto 15]. Disponible en: http://www.dgepi.salud.gob.mx/Anuarios de morbilidad
Cabello C, Manjarrez ME, Olvera R, Villalba J, Valle L, Paramo I. Frequency of viruses associated with acute respiratory infections in children younger than five years of age at a locality of Mexico city. Mem Inst Oswaldo Cruz 2006;101:21-24.
Noyola DE, Rodriguez-Moreno G, Sanchez-Alvarado J, Martínez-Wagner R, Ochoa-Zavala JR. Viral etiology of lower respiratory tract infections in hospitalized children in Mexico. Pediatr Infect Dis J 2004;23:118-123.
Noyola DE, Arteaga-Domínguez G. Contribution of respiratory syncytial virus, influenza and parainfluenza viruses to acute respiratory infections in San Luis Potosí, Mexico. Pediatr Infect Dis J 2005;24:1049- 1052.
Noyola DE, Zuviri-González A, Castro-García JA, Ochoa-Zavala JR. Impact of respiratory syncytial virus on hospital admissions in children younger than 3 years of age. J Infect 2007;54:180-184.
Ayora-Talavera G, Gongora-Bianchi RA, Lopez-Martinez I, Moguel- Rodríguez W, Pérez-Carrillo H, Vázquez-Zapata V, et al. Detection of human influenza virus in Yucatan, Mexico. Rev Invest Clin 2002;54:410-414.
Manjarrez ME, Rosete DP, Rincon M, Villalba J, Cravioto A, Cabrera R. Comparative viral frequency in Mexican children of 5 years of age with and without upper respiratory symptoms. J Med Microbiol 2003;52:579-583.
Noyola DE, Alpuche-Solis AG, Herrera-Diaz A, Soria-Guerra RE, Sánchez-Alvarado J, López-Revilla R. Human metapneumovirus infections in Mexico: epidemiological and clinical characteristics. J Med Microbiol 2005;54:969-974.
Talavera GA, Mezquita NE. Human metapneumovirus in children with influenza-like illness in Yucatan, Mexico. Am J Trop Med Hyg 2007;76:182-183.
Mascareñas-de los Santos C, Vera-García H, Mantilla-Figueroa Z, Calderon-Cruz E, Penagos M, Lopez I, et al. Agentes etiológicos de bronquiolitis en niños. Revista de Enfermedades infecciosas en Pediatría 2003;XVI:122-126.
López-Martínez I, Flores-León R, Fuentes-Rosas E. Infecciones respiratorias agudas (IRAS) de etiología viral en México. Epidemiología
18(41). Secretaría de Salud, México [consultado 2010 enero 20]. Disponible en: http://www.dgepi.salud.gob.mx/boletin/2001/sem41/edit41.PD
Straliotto SM, Siqueira MM, Machado V, Maia TM. Respiratory viruses in pediatric intensive care unit: prevalence an clinical aspects. Mem Inst Oswaldo Cruz 2004;99:883-887.
Viegas M, Barrero PR, Maffey AF, Mistchenko AS. Respiratory viruses seasonality in children under five years of age in Buenos Aires, Argentina: a five-year analysis. J Infect 2004;49:222-228.
Artiles-Campelo F, Pérez-González M del C, Caballero-Hidalgo A, Peña-López ML. Etiology of acute viral respiratory tract infections in children from Gran Canaria, the Canary Islands (Spain). Enferm Infecc Microbiol Clin 2006;24:556-561.
Freymuth F, Vabret A, Cuvillon-Nimal D, Simon S, Dina J, Legrand L, et al. Comparison of multiplex PCR assays and conventional techniques for the diagnostic of respiratory virus infections in children admitted to hospital with an acute respiratory illness. J Med Virol 2006;78:1498-1504.
Kahn J. Epidemiology of human metapneumovirus. Clinical Microbiol Reviews 2006;19:546-557.
Ordas J, Boga JA, Alvarez-Arguelles M, Villa L, Rodriguez-Dehli C, Oña M, et al. Role of metapneumovirus in viral respiratory infections in young children. J Clin Microbiol 2006;44:2739-2742.
Hamelin ME, Boivin G. Human metapneumovirus: a ubiquitous and long-standig respiratory pathogen. Pediatr Infect Dis J 2005;24:S203-S207.
Cody-Meissner H. Reducing the impact of viral respiratory infections in children. Infect Dis Clin N Am 2005;52:695-710.
Konig B, Konig W, Arnold R, Werchau H, Ihorst G, Forster J. Prospective study of human metapneumovirus infection in children less than 3 years of age. J Clin Microbiol 2004;42:4632-4635.
Weissbirch B, Neske F, Schubert J, Tollmann F, Blath K, Bessing K, et al. Frequent detection of bocavirus DNA in german children with respiratory tract infections. BMC Infect Dis 2006;6:109-115.
Naghipour M, Cuevas LE, Bakhshinejad T, Dove W, Hart CA. Human bocavirus in Iranian children with acute respiratory infections. J Med Virol 2007;79:539-543.
Allander T, Jartti T, Gupta S, Niesters HG, Lehtinen P, Osterback R, et al. Human bocavirus and acute wheezing in children. Clin Infect Dis 2007;44:904-910.
Williams J. The clinical presentation and outcomes of children infected with newly identified respiratory tract viruses. Infect Dis Clin N Am 2005;19:569-584.
Koetz A, Nilsson P, Linden M, van der Hoek L, Ripa T. Detection of human coronavirus NL63, human metapneumovirus and respiratory syncytial virus in children with respiratory tract infections in sout-west Sweden. Clin Microbiol Infect 2006;12:1089-1096.
Fleming DM, Pannell RS, Elliot AJ, Cross KW. Respiratory illness associated with influenza and respiratory syncytial virus infection. Arch Dis Child 2005;90:741-746.
Lee MS, Walker RE, Mendelman PM. Medical burden of respiratory syncytial virus and parainfluenza virus type 3 infection among US children. Implications for design of vaccine trials. Hum Vacc 2005;1:6-11.
Johannes F, Gariele I, Christian HLR, Volker S, Hans-Dieter F, Hidrun G, et al. Prospective population-based study of viral lower respiratory tract infections in children under 3 years of age (the PRI.DE study). Eur J Pediatr 2004;163:709-716.
Chavez-Bueno S, Mejias A, Jafri HS, Ramilo O. Respiratory Syncytial virus: old challenges and new approaches. Pediatric Annals 2005;34:62-68.
Shay DK, Holman RC, Newman RD, Liu LL, Stoput JW, Anderson LJ. Bronchiolitis associated hospitalization among United States children 1980-1996. JAMA 1999:282:1440-1446.
Murguia de Sierra T, Bustos E, Casasola-Flores J, Gómez-Barreto D. Role of respiratory syncytial virus in lower respiratory tract infections in a pediatric hospital in Mexico city. Bol Med Hosp Infant Mex 1995;52:17-22.
Centers for Disease Control and Prevention. Prevention and control of influenza. MMWR Morb Mortal Wkly Rep 2003;52(RR-8):1-36.
Principi N, Esposito S, Gasparini R, Marchisio P, Crovari P. Burden of influenza in healthy children and their households. Arch Dis Child 2004;89:1002-1007.
Henrickson KJ. Cost-effective use of rapid diagnostic techniques in the treatment and prevention. Pediatric Annals 2005;34:24-31.
Ellis JZ, Zambon MC. Molecular diagnosis of influenza. Rev Med Virol 2002;12:375-389.
Iskander M, Booy R, Lambert S. The burden of influenza in children. Curr Opin Infect Dis 2007;20:259-263.
Organización Mundial de la Salud. Información mundial de Influenza [monografía en internet] [consultado 2009 enero 3]. Disponible en: http:// gamapserver.who.int/GlobalAtlas/PDFFactory/FluNet/SummaryReport.asp
Kuypers J, Wright N, Ferrenberg J, Huang ML, Cent A, Corey L, et al. Comparison of real-time PCR assays with fluorescent-antibody assays for diagnosis of respiratory virus infections in children. J Clin Microbiol 2006;44:2382-2388.
Shen K, Zhaori G, Zweygberg-Wirgart B, Ying M, Grandien M, Wahren B, et al. Detection of respiratory viruses in nasopharyngeal secretions with immunofluorescence technique for multiplex screening-an evaluation of the Chemicon assay. Clin Diagnostic Virol 1996;6:147-154.