medigraphic.com
Federación Mexicana de Ginecología y Obstetricia, A.C.

2009, Number 03

Next >>

Ginecol Obstet Mex 2009; 77 (03)

Screening of metabolic syndrome in the perimenopause

Aguilar VZ, García LL

Language: Spanish
References: 19
Page: 123-127
PDF size: 42.33 Kb.


ABSTRACT

Background: There are few studies conducted in Mexico on increasing rates of cardiovascular diseases in postmenopausal patients with metabolic syndrome.
Objective: To determine frequency of metabolic syndrome in women of 40 to 55 years old, that are in perimenopause and go to the external consultation of the Materno Infantil Inguarán Hospital
Material and methods: We made transversal, observational, and prospective study, including women of 40 to 55 years old, that went to external consultation of the Materno Infantil Inguarán Hospital, since January to June 2007 (n=60). To all the patients it was taken them blood samples in uninformed stop to value glucose, triglycerides, HDL, pressure blood and Body Measure Index and wais-to-hip ratio.
Results: The patients went to the Hospital by gynecologic pathology. We found Metabolic Syndrome frequency and the abnormal factors were triglyceride, waist circumference. We found high frequency hypertrglyceridemia and central obesity.
Conclusions: In the perimenopause patients, to exist high frequency and predominance in the 40 and 50 years old, hers were asymptomatic. Before to be important to made screening in this patients, be cheap, and we can to prevent chronic disease such as Diabetes Mellitus Type 2 and Arterial Hypertension.
Increase quality of live in this group of patients.


REFERENCES

  1. Sherman S. Defining the menopausal transition. Am J Med 2005;118(Suppl. 12B):3S-7S.

  2. Wilson GM. Menopause. Clin Geriart Med 2003;19:483-506.

  3. Santoro N. The menopausal transition. Am J Med 2005;118(Suppl. 12B):8S-13S.

  4. Carr M. The Emergence of the metabolic syndrome with menopause. Endocrinol Metab Clin North Am 2003;88;6:2404-11.

  5. Cameron JA, Shaw JE, Zimmet PZ. The metabolic syndrome: prevalence in worldwide populations. Endocrinol Metab Clin N Am 2004;33:351-75.

  6. Chu MC, Cosper P, Orio F, Carmina E. Insulin resistance in postmenopausal women with metabolic syndrome and the measurements of adiponectin, leptin, resistin, and ghrelin. Am J Obstet Gynecol 2006;194:100-4.

  7. Natali A, Ferrannini E. Hypertension, insulin resistance and the metabolic syndrome. Endocrinol Metabol Clin N Am 2004;33:417-29.

  8. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486-97.

  9. Ferrara CM, Lynch NA, Nicklas BJ, Ryan AS, Berman DN. Differences in adipose tissue metabolism between postmenopausal and perimenopausal women. J Clin Endocrinol Metabol 2002;87;9:4166-70.

  10. Nigam A, Bourassa MG, Bortier A, Guertin MC, Tardif JC. The metabolic syndrome and its components and the long-term risk of death in patients with coronary heart disease. Am Hearth J 2006;151:514-21.

  11. Sutton-Tyrrell K, Wildman RD, Matthews, Chae C, et al. Sex hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the study of Women Across the Nation (SWAN). Circulation 2005;111:1242-9.

  12. Sowers M, Derby C, Jannausch ML, Torrens JI, Pasternak R. Insulin resitance, hemostatic factors, and hormone interactions in pre-and perimenopausal women: SWAN. J Clin Endocrinol Metabol 2003;88;10:4909-10.

  13. Kuschner FR, Roth LJ. Medical evaluation of the obese individual. Psychiatr Clin N Am 2005;28:89-103.

  14. Sowers M, Crawford SL, Cauley JA, Stein E. Association of lipoprotein(a), insulin, resistance, and reproductive hormones in a multiethnic cohort of pre-and perimenopausal women (the SWAN Study). Am J Cardiol 2003;92:533-7.

  15. Piché ME, Weisnagel SJ, Corneau L, Nadeau A, et al. Contribution of abdominal visceral obesity and insulin resistance to the cardiovascular risk profile of postmenopausal women. Diabetes 2005;54:770-7.

  16. Sites CK, L´Hommedieu GD, Toth MJ, Brochu M, et al. The effect of hormone replacement therapy on body composition, body fat distribution, and insulin sensitivity in menopausal women: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metabol 2005;90;5:2701-7.

  17. Goodrow JG, L´Hommedieu GD, Danong B, Sites CK. Predictors of worsening insulin sensitivity in postmenopausal women. Am J Obstet and Gynecol 2006;194:355-61.

  18. Wamala PS, Lynch J, Horsten M, Mittleman MA, et al. Education and metabolic syndrome in women. Diabetes Care 2003;22;12:1999-2003.

  19. Aguilar-Salinas CA, Rojas R, Gómez-Pérez FJ, Valles V, Ríos-Torres JM, et al. Analysis of the agreement between the World Health Organization criteria and the National Cholesterol Education Program-III definition of the metabolic syndrome: results from a population-based survey. Diabetes Care 2003;26:16-21.




2020     |     www.medigraphic.com