Baeza-Herrera C, López-Castellanos L, Escobar-Izquierdo MA, López-Castellanos G, González-Mateos T

Language: Spanish
References: 30
Page: 324-328
PDF size: 499.41 Kb.

ABSTRACT

Introduction. Acute appendicitis is a common condition usually requiring emergency surgery. The most common complication of appendectomy is postoperative sepsis. The average incidence of postoperative infection is around 30%. In order to minimize the incidence of postoperative sepsis various medical and surgical methods have been tried but results have not been homogeneous. In order to assess the efficacy of an antibiotic a prospective, randomized, double-blind clinical study was performed to compare the efficacy of a short–term postoperative treatment with phosphomycin versus the traditional method with metronidazole-amikacine during 10 days to prevent postoperative septic complications of emergency appendectomy for nonperforated appendicitis.
Results. We studied 30 patients en each group. The first, (group A) was managed with phosphomycin for three days; the second, (group B) was treated with traditional medications. Both groups had the same results. However, group A had monocitosis and eosinophilia with statistical significance (p‹0.047 and p‹0.017 respectively).
Conclusion. Phosphomycin and the conventional association of metronidazole-amikacine give the same results to prevent postappendectomy complications in children.

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