2009, Number 32
Study of the natural vs sintetic hidroxiapatite in the biological acceptation and bone regeneration efficacy in animal model
Téllez JH, Guerrero ÁF, Torres BJM
Language: Spanish
References: 0
Page: 533-536
PDF size: 328.78 Kb.
ABSTRACT
Comparative study in the bone regeneration of the natural (HAN) and syntetic hidroxyapatite (HAS) bone defects on a animal models. The biological acceptation was analize and its intervention in boneregeneration, radiographic, macroscopic and histocally was ewvaluated.The New Zealand rabbits were manipulated quirurgically, a bone defect was created on posteriorextremites, in the right ectremity HAN and HAS in the left extremity.
After 3, 6, and 9 weeks radipgraphic controls were made then the rabbits were sacrified and dissected to process them by macroscopic observation and histological process.
HAN group presented reabsortion and osteoblasic cellular activity increasing the bone neoformation with the osteocyte formation. The HAS syntetic seems like a inert material is incapsulated with a fibroblastic activity obturating the bone defect.
We conclude that HAN is an osteoconductor that accelerated bone proccess regeneration like an union to the neoformation bone cells, HAS seems like a inert material is incapsulated with a fibroblastic activity obturating the bone defect.