The clinical effectiveness on periodontal bone defects treatmente of plasma rich in growth factors (PRGF) combine with tricalcium phosphate (&#946;-TCP)

América Lince de León; Fermín Guerrero del Ángel; Héctor Téllez Jiménez; Lisbeth Maritza de la Portilla Ramírez; José Martín Torres Benítez

2009, Number 30

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Oral 2009; 10 (30)

The clinical effectiveness on periodontal bone defects treatmente of plasma rich in growth factors (PRGF) combine with tricalcium phosphate (β-TCP)

Lince de LA, Guerrero ÁF, Téllez JH, Portilla RLM, Torres BJM

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Language: Spanish
References: 0
Page: 498-503
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ABSTRACT

Objective: To evaluate the clinical effectiveness on periodontal Bone Defects Treatment of Plasma Rich in Growth Factors (PRGF) combine with Tricalcium Phosphate (β-TCP).
Methods: Fifteen patients with 37 periodontal effects, divided in two groups: 19 experimental (β-TCP-PRGF) and 18 controls (β-TCP). Patients with an initial pocket depth of 5mm and radiographic evidence of the effect were included. Patients were appointed for 2, 4, 8 and 12 weeks period appointments where gingival resorption and dental movement measurements were made. After 12 weeks the pocket depth, mobility, gingival resorption and relative clinical insertion level were take so that later reopening could be done for verifying the new depth of the vertical defect.
Results: Probing bleeding reduced 58% on control goup and 38% on experimental. Dental mobility, probing depth and plaque index reduced on both groups. Gingival resorption increased in all groups as the insertion lost was on the experimental group only. A reported decrease of defect depth on experimental group of 2.2mm compared with the 1.8mm of the control group. Changes radiographically observed of an 84% of the experimental group in contrast of the 16% of the control group.
Discussion: PRGF application as an alternative of the periodontal surgery therapy has been reported just on a few papers. Most of whic evaluate the combination of three different therapies including RTG, PRGF and bone insertion (Lekovic, Camargo), where the RTG had no clinical benefits, which means that the PRGF addition to the bone insertion may promote the clinical effects of the triple combination. Thus, the objective of this study was to evaluate the clinical effectiveness of PRGF combined with β-TCP on periodontal bone defects treatment. This study as the Nevins one, found an increase on gingival resorption after three months of combined treatment PRGF and β-TCP compared with the β-TCP treatment.