2010, Number 3
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Vet Mex 2010; 41 (3)
Clinical efficacy of parenteral vs ophthalmic florfenicol for the treatment of infectious bovine keratoconjunctivitis
Zamora QMA, Aguilar AJ, Sumano LH
Language: English/Spanish
References: 13
Page: 219-225
PDF size: 257.52 Kb.
ABSTRACT
The clinical and bacteriological efficacy, the quantity of mg and florfenicol treatment length for infectious bovine keratitis (
Moraxella bovis) was assessed using either the parenteral administration of florfenicol (PF), or the ophthalmic administration of the drug in spray (OF). Sixty four cows and heifers were randomly divided into the two referred treatments. All animals were cured, however, the OF group required a mean of 378 mg/bovine and 12 days of treatment, while the PF group needed 22 800 mg/bovine (3.8 treatments per bovine) and 7.6 days. Although 100% efficacy was obtained in both groups cost-benefit ratio in the OF group is pondered
REFERENCES
BILLINGS FS, ADKINS TR. Contagious inflammation of the cornea in cattle keratitis. Bull Agric St Nebr 1889; 3: 247-252.
CHANDLER RL, BAPTISTA PJ, TURFREV B. Studies on the pathogenicity of Moraxella bovis in relation to infectious bovine keratoconjunctivitis. J Comp Pathol 1979; 89: 441-448.
BROWN MH, BRIGHTMAN AH, FENWICK BW, RIDER MA. Infectious bovine keratoconjunctivitis: a review. .J Vet Intern Med 1998; 12:259-266.
BEDFORD PG. Infectious bovine keratoconjunctivitus. Vet Rec 1976; 98:134-135.
SMITH JA, GEORGE LW. Treatment of acute ocular Moraxella bovis infections in calves with a parenterally administered long-acting oxytetracycline formulation. Am J Vet Res 1985; 46: 804-807.
ANDREWS AH., BLOWEY RW, BOYD H, EDDY RG. Bovine medicine diseases and husbandry of cattle. 2d ed. Oxford: Blackwell Publishing, 2004.
SHRYOCKA TR, WHITEA DW, WERNERB CS. Antimicrobial susceptibility of Moraxella bovis. Vet Microbiol 1998; 61: 305-309.
STARKE A, EULE C, MEVER H, IM WINKEL C, VERSPOHL J, REHAGE J. Efficacy of intrapalpebral and intramuscular application of oxytetracycline in a natural outbreak of infectious bovine kertoconjunctivitis (IBK) in calves. Dtsch Tierarztl Wochenschr 2007; 114: 219-24.
ANGELOS JA, DUEGER EL, GEORGE LW, CARRIER TK, MIHAL JE, COSGROVE SB et al. Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis. J Am Vet Med Assoc 2000; 216: 62-64.
DUEGER EL, ANGELOS JA, COSGROVE SB, JOHNSON JC, GEORGE LW. Efficacy of florfenicol in the treatment of experimentally induced infectious bovine keratoconjunctivitis. Am J Vet Res 1999; 60:960- 964.
PUGH GW, HUGHES DE. Infectious bovinekeratoconjunctivitis: Moraxella bovis as the sole etiologic agent in winter epizootic. J Am Vet Med Assoc 1972; 161: 481-486.
SUMANO LH, OCAMPO CL. Farmacología Veterinaria. 3ª ed. México DF: McGraw-Hill Interamericana, 2006.
LANE VM, GEORGE LW, CLEAVER DM. Efficacy of tulathromycin for treatment of cattle with acute ocular Moraxella bovis infections. J Am Vet Med Assoc 2006; 229: 557-561.