Tena SML, Salinas LC, Rembao BD, Vega R, Castillejos LM

Language: Spanish
References: 30
Page: 112-117
PDF size: 146.44 Kb.

ABSTRACT

Amyloid is a fibrilar material that deposits extracellularly in different organs and in different circumstances. It is classified according to its biochemical components and precursors. Study design: a descriptive, retrospective, study was performed to identify the amyloid deposition in choroid plexus tumors. Results: we studied 37 cases of choroid plexus tumors. 27 were papillomas and 10 carcinomas; 26 were females and 11 were males. Amyloid was present in 40.5%, 27% in papillomas and 13.5% in carcinomas (p.483), from which 12 cases (32.4%) were female and 3 (8.1%) were male (p.342). Two of the carcinomas presented abundant amyloid, one of them also presented bone metaplasia; Other features were; fibrosis in 70.3%, hemorrhage in 62.2%, gross vessels in 24.3% and inflammatory infiltration in 54.1% (p.066). The clinical post surgical follow up was up to 120 months, however, in the cases that presented amyloid was up to 40 months. We did not find any relationship between amyloid deposition and histological type, or the age of the patients. Conclusions: it is well known that inflammatory infiltration has been associated to amyloidosis, which could be a protection or defence mechanism in choroid plexus tumors. Therefore, we suggest that the association between amyloid and inflammatory infiltration have a direct relationship with the biological behavior of the tumor.

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