Guajardo-Lara CE, González-Martínez PM, Ayala-Gaytán JJ

Language: Spanish
References: 16
Page: 157-161
PDF size: 120.07 Kb.

ABSTRACT

Objective. Determine antibiotic resistance of community-acquired uropathogen Escherichia coli and infer therapeutic options. Material and Methods. E. coli strains isolated from urine during a one-year period were studied. Identification and susceptibility tests were performed. Results. A total of 652 isolates were included from patients in two institutions, a healthcare clinic 303 (46.5%) and a hospital 349 (53.5%). The antimicrobials with higher resistance rates were ampicillin 67.2%, trimethoprim-sulfametoxazole 59.2%, cefazolin 35.6% and ciprofloxacin 24.7%. Conclusions. Resistance to trimethoprim-sulfamethoxazole and ciprofloxacin used for empiric treatment in community urinary infections is high, and there are few available treatment options.

REFERENCES

1. Foxman B, Ki M, Brown P. Antibiotic resistance and pyelonephritis. Clin Infect Dis 2007;45:281-283.

2. Foxman B, Brown P. Epidemiology of urinary tract infections: transmission and risk factors, incidence and cost. Infect Dis Clin North Am 2003;17:227-241.

3. Warren JW, Abrutyn E, Hebel JR, Johnson JR, Schaeffer AJ, Stamm WE. Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women. Infectious Disease Society of America (IDSA). Clin Infect Dis 1999;29:745-758.

4. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; Sixteenth Informational Supplement. M100-S16. Wayne (PA): Clinical and Laboratory Standards Institute, 2006.

5. Alós JI, Serrano MG, Gómez- Garcés JL, Perianes J. Antibiotic resistance of Escherichia coli from community-acquired urinary tract infections in relation to demographic and clinical data. Clin Microbiol Infect 2005;11:199-203.

6. Andreu A, Alós JI, Gobernado M, Marco F, De la Rosa M, García-Rodríguez JA. Etiología y sensibilidad a los antimicrobianos de los uropatógenos causantes de la infección urinaria baja adquirida en la comunidad. Estudio nacional multicéntrico. Enferm Infecc Microbiol Clin 2005;23:4-9.

7. Ti TY, Kumarasinghe G, Taylor MB, Tan SL, Ae A, hua C et al. A. What is true community-acquired urinary tract infection? Comparison of pathogens identified in urine from routine outpatient specimens and from community clinics in a prospective study. Eur J Clin Microbiol Infect Dis 2003;22:242-245.

8. Dromigny JA, Nabeth P, Juergens-Behr A, Perrier-Gros-Claude JD. Risk factors for antibiotic-resistant Escherichia coli isolated from community-acquired urinary tract infections in Dakar, Senegal. J Antimicrob Chemother 2005;56:236-239.

9. Andrade SS, Sader HS, Jones RN, Pereira AS, Pignatari ACC, Gales AC. Increased resistance to first-line agents among bacterial pathogens isolated from urinary tract infections in Latin America: time for local guidelines? Mem Inst Oswaldo Cruz 2006;101:741-748.

10. Arreguín V, Cebada M, Simón JS, Sifuentes-Osornio J, Bobadilla-del Valle M, Macías AE. Microbiología de las infecciones urinarias en pacientes ambulatorios. Opciones terapéuticas en tiempos de alta resistencia a los antibióticos. Rev Invest Clin 2007;59:239-245.

11. Cornejo-Juárez P, Velásquez-Acosta C, Sandoval S, Gordillo P, Volkow-Fernández P. Patrones de resistencia bacteriana en urocultivos en un hospital oncológico. Salud Publica Mex 2007;49:330-336.

12. Hernández- Blas F, López- Carmona JM, Rodríguez-Moctezuma JR, Peralta-Pedrero ML, Rodríguez-Gutiérrez RS, Ortiz-Aguirre AR. Frecuencia de bacteriuria asintomática en embarazadas y sensibilidad antimicrobana in vitro de los uropatógenos. Ginecol Obstet Mex 2007;75:325-331.

13. Taur Y, Smith MA. Adherence to the Infectious Diseases Society of America Guidelines in the treatment of uncomplicated urinary tract infections. Clin Infect Dis 2007;44:769-774.

14. Gupta K, Saham DF, Mayfield D, Stamm WE. Antimicrobial resistance among uropathogens that cause community-acquired urinary tract infections in women: A nationwide analysis. Clin Infect Dis 2001;33:89-94.

15. Naber KG. Treatment options for acute uncomplicated cystitis in adults. J Antimicrob Chemother 2000; 46 Suppl 1:23-27.

16. Gupta K, Hooton TM, Roberts PL, Stamm WE. Short -course nitrofurantoin for the treatment of acute uncomplicated cystitis in women. Arch Intern Med 2007;167:2207-2212.