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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2010, Number 2

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Rev Biomed 2010; 21 (2)

Metabolic Syndrome and its correlation with serum levels of urea, creatinine and uric acid in adults from Veracruz

Campos-Mondragón MG, Oliart-Ros RM, Méndez-Machado GF, Angulo-Guerrero O

Language: Spanish
References: 26
Page: 67-75
PDF size: 138.04 Kb.


ABSTRACT

Objective. The aim was to determine the prevalence of metabolic syndrome (MS) and to correlate its components with the serum levels of urea, creatinine and uric acid, in adults from Veracruz.
Materials and Methods. It was assessed 105 people with social health insurance non-hospitalized from IMSS UMAE No. 14. The mean age was 45.8 ±13.5 years. After 12-hour fasting period a blood sample was taken to the following serum determinations: glucose, urea, creatinine, uric acid, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides. The anthropometric parameters, blood pressure and heart rate were assessed. MS was defined according to ATP-III and IDF.
Results. The 60% of adults had MS, most of them (30.3%) were 45-64 years old. Abdominal obesity and low HDL-cholesterol, were the most frequent alterations (97.1% and 69.5%). The 31.4% of the sample was found with hyperuricemia. The serum level of uric acid was directly correlated with glucose (r=0.27 p ‹0.05), sistolic (r= 0.20 p ‹0.05) and diastolic blood pressure (r= 0.19 p ‹0.05). Uric acid was inversely associated with HDL-cholesterol (r=-0.39 p ‹0.05). Urea showed positive relation with sistolic (r= 0.33 p ‹0.05) and BUN/creatinine with diastolic blood pressure (r= 0.20 p ‹0.05).
Conclusion. The high frequency of MS in these adults was determined by the abdominal obesity and the hipoalphalipoproteinemia. The MS was associated to hyperuricemia which was evident in the third of the sample.


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