medigraphic.com

2010, Number 1

<< Back Next >>

Rev Mex Ing Biomed 2010; 31 (1)

Biomineralization onto zinc aluminate nanostructured ceramic

Álvarez-Pérez MA, García-Hipólito M,de la Fuente-Hernández J, Suárez-Franco JL, Juárez-Islas JA, Álvarez-Fregoso O

Language: Spanish
References: 29
Page: 6-14
PDF size: 335.69 Kb.


ABSTRACT

In recent years, the nanomaterials have been proposed like a new option to increase the cellular response onto dental and orthopedic implants. With this in mind, it has been developed a study to investigate the effect of the nanotopography of one ceramic compound on the biomineralization process. In this case we use zinc aluminate films, deposited by spray pyrolysis technique, with nanometer sized morphologies. The obtained results, when culture osteoblastic cells onto nanoceramics, indicated that the nanometer sized surface of the proposed material increased the cellular adherence, as compared with the surfaces of the reference material. From the above-mentioned result, it can be deduced that the nanometer sized surface changes the properties of the ceramic material to behave as a material with a bioactive surface. This bioactivity is manifested with the increment in the biomineralization of the extracellular matrix and in the orderly rise of the mineral tissue deposited. According to the obtained results, we propose to the zinc aluminate films like a biocompatible ceramic which provides a similar nanometer sized ambient comparable with that of the human bone where biomineralization is favored. Such films can be applied on the implant materials in the dental and orthopedic area in our country.


REFERENCES

  1. Rouahi M, Champion E, Hardouin P, Anselmo K. Quantitative kinetic analysis of gene expression during human oteoblastic adhesion on orthopaedic materials. Biomaterials 2006; 27: 2829-2844.

  2. Burg K, Porter S, Kellam JF. Biomaterials developments for bone tissue engineering. Biomaterials; 2000, 21: 2347-2359.

  3. Meyer U, Joos U, Weissman HP. Biological and biophysical principles in extra corporal bone tissue engineering Part I. Int J Oral Maxillofac Surg 2004; 33: 325-332.

  4. Storrie H, Stupp SI. Cellular response to zinc-containing organoapatite: An in vitro study of proliferation, alkaline phosphatase activity and biomineralization. Biomaterials 2005; 26: 5492-5499.

  5. Sakiyama-Elbert SE, Hubbell JA. Functional biomaterials: design of novel biomaterials. Ann Rev Mat Res 2001; 31: 183-201.

  6. Brunski JB, Puleo DA, Nanci A. Biomaterials and biomechanics of oral and maxillofacial implants: current status and future developments. Int J Oral Maxillofac Implants 2000; 15: 15-46.

  7. Dalby MJ, Di Silvio L, Davies GW, Bonfield W. Surface topography and HA filler volume effect on primary human osteoblasts in vitro. J Mat Sci Mater Med 2000; 11: 805-810.

  8. Lincks J, Boyan BD, Blanchard CR, Lohmann CH, Liu Y, Cochran CD, Dean DD, Schwartz Z. Response of MG63 osteoblast-like cells to titanium and titanium alloy is dependent on surface roughness and composition. Biomaterials 1998; 19: 2219-2232.

  9. Masaki Ch, Schneider GB, Zaharias R, Seabold D, Stanford C. Effects of implant surface microtopography on osteoblasts gene expression. Clin Oral Impl Res 2005; 16: 650-656.

  10. Dalby MJ, Giannaras D, Riehle MO, Gadegaard N, Affrossman S, Curtis ASG. Rapid fibroblasts adhesion to 27 nm high polymer demixed nano-topography. Biomaterials 2004; 25: 77-83.

  11. Stevens MM, George JH. Exploring and engineering the cell surface interface. Science 2005; 310: 1135-1138.

  12. Liu H, Webster TJ. Nanomedicine for implants: A review of studies and necessary experimental tools. Biomaterials 2007; 28: 354-369.

  13. Webster TJ, Hellenmeyer EL, Price RL. Increased osteoblasts functions on theta + delta nanofiber alumina. Biomaterials 2005; 26: 953-960.

  14. Lenhert S, Meier MB, Meyer U, Chi L, Weissman HP. Osteoblasts alignment, elongation and migration on grooven polyestyrene patterned by Langmuir-Blodgett lithography. Biomaterials 2004; 26: 563-570.

  15. Wang JH, Yao CH, Chuang WY, Young TH. Development of biodegradable polyesterurethane membranes with different surface morphologies for culture of osteoblasts. J Biomed Mater Res 2000; 15: 761-770.

  16. Rice JM, Hunt JA, Gallagher JA, Hanarp P, Sutherland DS, Gold J. Quantitative assessment of the response of primary derived human osteoblasts and macrophages to a range of nanotopography surfaces in a single culture model in vitro. Biomaterials 2003; 24: 4799-4818.

  17. Liu Y, Cooper PR, Barralet JE, Shelton MR. Influence of calcium phosphate crystal assemblies on the proliferation and osteogenic gene expression of rat bone marrow stromal cells. Biomaterials 2007; 8: 1393-1403.

  18. Dalby MJ, McCloy D, Robertson M, Agheli H, Sutherland D, Affossman S, Oreffo RCO. Osteoprogenitor response to semi-ordered and random nanotopographies. Biomaterials 2006; 27: 2980-2987.

  19. Price RL, Haberstroh KM, Webster TJ. Enhanced functions of osteoblasts on nanostructured surfaces of carbon and alumina. Med Biol Eng Comput 2003; 41 (3): 372-375.

  20. Oliveira PT, Nanci A. Nanotexturing of titanium-based surfaces up regulates expression of bone sialoprotein and osteopontin by cultured osteogenic cells. Biomaterials 2004; 24: 403-413.

  21. Hyman GE, Engvall E, A´Hearn E, Barnes D, Pierschbacher M, Rouslathi E. Cell attachment on replicas of SDS polyacrylamide gels reveals two adhesive plasma proteins. J Cell Biol 1982; 95: 20-23.

  22. Power diffraction file card No. 5-669, International Center for Diffraction Data, 1990.

  23. García-Hipólito M, Corona-Ocampo A, Alvarez-Fregoso O, Martínez E, Guzmán-Mendoza J, Falcony C. Characterization of ZnAl2O4: Tb luminescent films deposited by ultrasonic spray pyrolysis technique. Phys Stat Sol (a), 2004; 201(1): 72-79.

  24. Tarjeta de difracción: Power diffraction file card: ICCD-09-0432, 1997.

  25. Edington JW. Practical microscopy in materials science. Ed. MacMillan, Vol. 2, 1975.

  26. Webster TJ, Hellenmeyer EL, Price RL. Increased osteoblasts functions on theta+delta nanofiber alumina. Biomaterials 2005; 26: 953-960.

  27. Landis WJ. An overview of vertebrate mineralization with emphasis on collagen-mineral interaction. Gravit Space Biol Bull 1999; 12: 15-26.

  28. Anselme K. Osteoblast adhesion on biomaterials. Biomaterials 2000; 21: 667-681.

  29. Boyan BD, Lohmann CH, Dean DD, Sylvia VL, Cochran DL, Schwartz Z. Mechanism involved in osteoblast response to implant surface morphology. Annu Rev Mater Res 2001; 31: 357-371.




2020     |     www.medigraphic.com